What is inositol hexaphosphate (IP6) and myo-inositol? Are they helpful in treating cancer or other conditions?

Answer:

Inositol hexaphosphate (IP6), more commonly known as phytic acid or phytate (the salt form), is a naturally-occurring compound. It is a source of phosphate in many plants and is abundant in foods such as cereals, grains and legumes.

IP6 is not digestible by people; in fact, it can chelate minerals in the gut, inhibiting their absorption.

IP6 alone does not appear to have been used in any clinical studies. However, it has been used in combination with myo-inositol (also known as inositol) in preliminary research to reduce side effects of cancer therapy in women with breast cancer. There is one report of this combination used by a man with advanced skin cancer who, as reported by his doctors at the Mayo Clinic, entered remission.

Myo-inositol itself has been used for many other conditions, most notably polycystic ovary syndrome (PCOS), as well as depression, panic disorder and bipolar disorder, with some evidence of benefit.

Sign in for details about what these studies have shown, including information about dosage and safety, and learn how marketed form of inositol differ.

Note: Do not confuse inositol hexaphosphate with inositol hexanicotinate — a form of niacin found in some supplements.