Can any supplements be used to reduce inflammation in people sensitive to NSAIDs such as ibuprofen, high-dose aspirin, or naproxen?

I find it funny how my experience and experience I've seen from others is so much different from the studies done.

For me, when I stopped glucosamine/chondroitin/MSM supplements, the arthritis in my hands was so bad I had to take NSAIDS every day. And that only reduced the pain while it was active, did not make it stop. Only took a week or 2 for the supplements to start working again. Now, I can spend 12 to 15 hours at times on the computer with arthritis (managed by supplements) and not have any pain or need for NSAIDs. And stairs don't bother my knees anymore.

A couple people had told me glucosamine completely fixed their knee joint pain and stiffness.

My vet recommended a Vetri Science (no affiliation) for joints which has many things included in the joint supplement reviews. It made a huge difference in my cats. And one of the cats it helped didn't even have arthritic joint pain, but a pinched nerve in their spine.

I use Arnica cream to relieve muscle pain in my knees.

Years ago, I developed an extreme allergic reaction to Motrin (Ibuprophen)--giant hives and facial pain after I was handed a couple of Motrin after a root canal. Unaware Motrin may cause facial pain, my dentist prescribed MORE Motrin, finally resulting in difficulty breathing and, days later, giant hives. I went to ER in extreme respiratory distress where small injections of ephrinephrine finally stopped my extreme allergic reactions. I was hospitalized for 3 days. For many years, I've used curcumin, ginger, Boswellia, Arnica, Feverfew/other natural remedies as needed. Anyone taking Ibuprophen who develops a rash or difficulty breathing should know about this potentially deadly allergy--as should all medical personnel who don't always read pkg. warnings (which, themselves, are often inadequate). Get medical help immediately for any breathing problems or unusual rashes when taking Ibuprophen--or any other med. And show pkg. to your physician. Sadly, medical personnel are often unaware of these allergies --and may brush concerns aside. Remain persistent in educating others, as you'll be saving lives!

Thank you for this article. My husband almost died, his eyes rolled up and he was out when the paramedics took him away, from an aspirin. He had adult onset asthma and then nasal polyps (removed) which, I later learned forms a syndrome with NSAID allergy. NO doctor warned us of the possibility of NSAID allergy. This was at least 20 years ago, so maybe they didn't know. He has not taken any NSAID since on the advice of doctors. His infrequent migraine attacks totally disappeared more than 10 years ago, so he rarely needs pain relievers. Pain relief was a big problem when he had back surgery, as he started hallucinating and thinking I was trying to kill him, from narcotic pain medication. He's 76. I write this so it may help someone with asthma and nasal polyps avoid nearly dying. We simply don't have pain relief medication that is not dangerous. I hope someone will develop some.