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CL Answer

Can any supplements improve or worsen symptoms of fibromyalgia?

Find out if any supplements may help improve fibromyalgia symptoms, learn which supplements do not seem beneficial, and find out if any supplements worsen symptoms.

Woman holding sore back

Clinical Update

9/03/2021

Fibromyalgia After COVID

How common is fibromyalgia (widespread musculoskeletal pain) after COVID-19? Find out what a study showed.

Clinical Update

1/18/2014

Vitamin D Helps Fibromyalgia

Fibromyalgia is an inflammation of the muscle and soft tissue which causes pain and fatigue. A recent study found that giving vitamin D reduced the pain associated with fibromyalgia. For details about the dose and target vitamin D blood level in the study, as well as our tests of vitamin D supplements, see the updated  Vitamin D Supplements Review >>   

Clinical Update

2/02/2024

Thiamin for Fibromyalgia?

Can taking thiamin reduce symptoms of fibromyalgia? Find out in the Thiamin section of our B Vitamin Supplements Review. Also see our Top Picks among B vitamins.

Also see: Can any supplements improve or worsen symptoms of fibromyalgia?

Product Review

Iron Supplements Review (Iron Pills, Liquids and Chews)

See Which Iron Supplements Are CL's Top Picks for Different Needs

Product Review

Vitamin D Supplements Review (Including Calcium, Magnesium, Vitamin K, and Boron)

Find the Best Vitamin D Supplement and Avoid Problems

Vitamin D Review 2024

Product Review

Acetyl-L-Carnitine Supplements Review

Choose the Best Acetyl-L-Carnitine Supplement. Don't Overpay! CL Identifies Quality Acetyl-L-Carnitine Supplements at the Best Value.

Acetyl-L-Carnitine Supplements Tested by ConsumerLab.com

Product Review

L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review

Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.

L-Tryptophan and 5-HTP (5-Hydroxy-L-tryptophan) Supplements Reviewed By Consumerlab.com

CL Answer

What is CELLFOOD and is it a healthy supplement?

Learn more about CELLFOOD (NuScience Corporation), including if the claims to improve athletic performance, fibromyalgia, weight loss, and cancer are true.

What is CELLFOOD

CL Answer

What is Pycnogenol, does it work, and is it the same as other pine bark extracts?

Learn more about Pycnogenol, including evidence from clinical studies on blood clots, osteoarthritis, cognition, vision, tinnitus, and the skin and safety.

Pine bark extract

Clinical Update

5/19/2013

Creatine for Fibromyalgia

A new study shows that creatine might have a role in boosting muscle strength in patients with fibromyalgia. Get the details, plus quality ratings for creatine supplements in our updated Muscle Enhancers (Creatine and Branched Chain Amino Acids) Review >>

Clinical Update

1/10/2017

CoQ10 for Fibromyalgia

CoQ10 reduced symptoms of anxiety and depression in people with fibromyalgia, according to a preliminary study. Get the details, including dosage, in the "What It Does" section of the CoQ10 and Ubiquinol Supplements Review >>

Clinical Update

8/10/2019

CoQ10 for Fibromyalgia?

A recent study evaluated whether CoQ10 improved symptoms in patients with fibromyalgia when added to standard prescription treatment with pregabalin (Lyrica). See the results, and learn more about what CoQ10 can and cannot do in the What It Does section of the CoQ10 and Ubiquinol Supplements Review. Also see our Top Picks for CoQ10 and ubiquinol.

Clinical Update

11/17/2018

Melatonin for Fibromyalgia

Daily melatonin supplementation has been found to decrease pain and improve other symptoms of fibromyalgia. For details, see the What It Does section of the Melatonin Supplements Review. (Also see our Top Picks for melatonin.)

Clinical Update

2/13/2021

Vitamin D for Fibromyalgia?

Does vitamin D supplementation help women with fibromyalgia? See what a new study found in the What It Does section of the Vitamin D Supplements Review. Also see our Top Picks for vitamin D.

Clinical Update

3/14/2021

Fibromyalgia Supplement?

Pycnogenol (French pine bark extract) was recently reported to reduce muscle pain and fatigue in people with fibromyalgia, but how strong is the evidence?

Clinical Update

5/22/2021

Fibromyalgia Risk With Iron Deficiency Anemia?

A recent study suggests a link between iron deficiency anemia and fibromyalgia, particularly in women. Get the details in the What It Does section of our Iron Supplements Review. Also see our Top Picks among iron supplements.

CL Answer

What are the health benefits of D-ribose and is it safe?

Find out if D-ribose supplementation is beneficial for heart failure, exercise performance, and fibromyalgia and learn if it is safe.

Two measuring scoops and capsules of D-ribose on black countertop

CL Answer

Does red and near infrared light therapy reduce pain, improve skin or cognition, or have other benefits? Is it safe?

Red light and near infrared light therapy devices are promoted for numerous conditions, including acne, fibromyalgia, pain, cognitive function and other uses. Find out if these devices work and if they are safe.

Woman using a red light device on her lower leg

Product Review

SAMe (S-adenosyl-methionine) Supplements Review

Choose the Best SAMe Supplement and Save Money

SAMe 2024 v2

Product Review

Magnesium Supplements Review (Including Calcium, Vitamins D & K, and Boron)

Find Out What Magnesium Does, Who Needs It, and Our Top Picks Among Supplements

Magnesium Review 2024

Product Review

B Vitamin Supplements Review (B Complexes, B6, B12, Biotin, Folate, Niacin, Riboflavin & More)

See Our Top Picks and Which 5 Failed Testing

B Vitamins Review 2024

Product Review

CoQ10 and Ubiquinol Supplements Review

Find the Best CoQ10 and Ubiquinol Supplements and Learn How They Differ

CoQ10 2024

Product Review

Muscle & Workout Supplements Review (Creatine and Branched-chain Amino Acids)

Do Creatine and BCAAs Really Improve Strength and Recovery?

Product Review

Reishi Mushroom Supplements Review

Find the Best Reishi Mushroom Supplement. See How Reishi Supplements Differ.

Reishi Mushrooms tested by ConsumerLab.com

Clinical Update

5/26/2023

D-Ribose for Energy?

D-ribose is promoted for increasing energy during exercise and reducing fatigue in people with fibromyalgia. But does it really work, and is it safe? Find out in our article about the health benefits of D-ribose.

Clinical Update

2/17/2015

Creatine Tested for Parkinson Disease

Taking creatine daily for at least five years did not slow the progression of Parkinson disease according to a recently reported study involving nearly 1,000 patients. For more details about the study, other studies with creatine (for strength, fibromyalgia, etc.), and our tests of creatine supplements, see the Product Review of Muscle Enhancers (Creatine and Branched-chain Amino Acids) >> 

Clinical Update

3/06/2025

Light Therapy for Acne?

A recent article in a prominent journal suggests that red and blue light therapy is effective for acne. But this contrasts with the conclusions of other experts. Find out why in our article about red light therapy, which also reviews the evidence for aging skin, hair growth, osteoarthritis, fibromyalgia, cognition, and other conditions.

CL Answer

Do any supplements, foods, or oils help reduce muscle pain, muscle cramps, or nighttime leg cramps?

Find out which supplements, and topical products such as magnesium creams, can help reduce muscle pain, leg cramps, and nighttime leg cramps, and which may worsen muscle cramps. Also, learn about vitamin and mineral deficiencies and common medications that can cause muscle cramps and nocturnal leg cramps.

Magnesium & Other Supplements for Muscle Pain & Cramps -- woman with leg cramp

CL Answer

Immuno 150: Does It Boost Immunity?

Immuno 150 by Exceptional Health Products is promoted for boosting the immune system, but does it work and is it worth its price? Find out.

Bottle of Immuno 150

Product Review

Melatonin Supplements Review

Trouble Sleeping? See CL's Tests of Melatonin Supplements and Top Picks.

Melatonin Review 2024

CL Answer

Which supplements help with arthritis?

Learn more about supplements for joint health, including products such as Wobenzym and Zyflamend and ingredients such as collagen, curcumin, devil's claw, glucosamine and chondroitin, hyaluronic acid, magnesium, omega-3 fatty acids, palmitoylethanolamide (PEA), SAMe, and others.

Supplements for Osteoarthritis and Rheumatoid Arthritis -- Women With Arthritic Hands

CL Answer

How does turmeric spice compare to curcumin (turmeric extract) in supplements? I sprinkle it on my foods and wonder if that's equivalent to taking a supplement.

What is the difference between turmeric spices used in the kitchen and turmeric supplements? Is sprinkling turmeric on my food equivalent to taking a turmeric supplement? ConsumerLab's answer explores this question.

Turmeric Spice vs. Turmeric Supplements

CL Answer

Do any supplements, like Nervive, help with nerve pain, like sciatica, diabetic neuropathy or postherpetic neuralgia?

Find out which supplements for nerve pain, including fish oil and alpha-lipoic acid, are effective for sciatica, diabetic neuropathy, or postherpetic neuralgia.

CL Answer

Capsimax for Weight Control: Does It Work & Is It Safe?

Capsimax, a cayenne pepper extract, is included in a number of supplements for weight loss. Find out if it works and if it's safe.

Chili peppers with capsimax

CL Answer

Is sublingual vitamin B-12, which is placed under the tongue and allowed to dissolve, really better than the pill form?

Learn the difference between sublingual vitamin B-12, vitamin B-12 pills and more through information including clinical evidence.

Sublingual B-12 vs. Vitamin B-12 Pills -- B-12 supplements

CL Answer

Does Prelief Help with Heartburn or Bladder Pain Caused By Acidic Foods?

Learn about Prelief, a product promoted to reduce acidity from foods and drinks that may cause bladder pain, frequent urination, heartburn, or indigestion. Discover what Prelief claims to do, the clinical evidence supporting its use, and important safety considerations.

Bottle of Prelief Caplets and Container of Prelief Powder

News Release

October 31, 2024

Best SAMe Supplements for Arthritis and Depression, According to ConsumerLab Tests

White Plains, NY, October 31, 2024—  SAMe (S-adenosyl-methionine) supplements may reduce joint pain, stiffness, and inflammation caused by osteoarthritis, as well as improve symptoms of depression.

News Release

July 31, 2018

Best L-Tryptophan and 5-HTP Supplements Identified by ConsumerLab -- ConsumerLab Tests Strength and Purity of Supplements for Sleep and Mood

White Plains, New York, July 31, 2018 — L-tryptophan supplements are often promoted to improve sleep and 5-HTP supplements to help with depression.

Recalls & Warnings

March 23, 2023

FDA Warns Herbal Vitality for Promoting Supplements to Treat Cold & Flu, Kidney Stones & More

On March 7, 2023, the FDA issued a warning letter to Herbal Vitality, Inc.

Recalls & Warnings

August 29, 2013

Seller of CELLFOOD Supplements Warned For Manufacturing Violations and Drug Claims

On August 1, 2013, the FDA issued a warning letter to supplement retailer Lumina Health Products, Inc.

Recalls & Warnings

April 23, 2013

Seller of Digestion, Thyroid and Vitamin D Supplements Warned For Drug Claims

On November 5, 2012, the FDA issued a warning letter to The Women's Health Institute at Texas following a review of the company's various websites which found statements made about Digest + SEB, Iodine Plus 2, and D5000 Vitamin D dietary supplements to be drug claims.

Recalls & Warnings

September 13, 2013

Metagenics Warned For Misbranding of Medical Foods and Drug Claims

On August 13, 2013, the FDA issued a warning letter to Metagenics, Inc.

Recalls & Warnings

December 11, 2020

FDA Warns Seller of Curcumin and Cholesterol Supplements

On November 20, 2020, the FDA issued a warning letter to Natures Boost LLC following a review of the company's websites, which found statements made about the company's products Blood Boost Formula and Turmeric Curcumin to be drug claims.

Recalls & Warnings

April 17, 2020

Seller of Vitamin D, MSM, Selenium & More Warned for Drug Claims

On March 31, 2020, the FDA issued a warning letter to KetoKerri LLC following a review of the company's website, which found statements made about some of the company's products, including Dr.

Recalls & Warnings

September 12, 2006

U.S. Marshalls Seize Supplements Promoted as Drugs

On September 6, 2005, the U.S. Food and Drug Administration (FDA) announced that, at its request, U.S. Marshals seized quantities of Ellagimax capsules, Coral Max capsules, Coral Max without Iron capsules, and Advanced Arthritis Support capsules distributed by Advantage Nutraceuticals L.L.C.

Recalls & Warnings

April 02, 2019

FDA Issues Strong Warnings to Sellers of CBD

On March 28, 2019, the FDA issued warning letters to three companies for making unsubstantiated claims about the health benefits of CBD (cannabidiol) products on their websites.

Recalls & Warnings

October 11, 2016

Seller of Glucosamine and Chondroitin Settles FTC Charges of False Advertising

On October 5, 2016, the FTC announced the sellers of the liquid glucosamine and chondroitin supplement Supple (Supple LLC) agreed to settle charges they made false claims about the product.

Recalls & Warnings

January 26, 2016

Seller of CoQ10, SAM-e, Vitamin D, and More Warned for Manufacturing Violations, Drug Claims

On January 15, 2016, the FDA issued a warning letter to Nutri-Dyn Midwest, Inc., following a facility inspection which found the company's products, including Cardioauxin BP, Zinc Lozenge, Oliver, Pau D'Arco, Petadolex, Chondro Jointaide, Dynagesic, SAMe-200, Gugulipid.

Recalls & Warnings

October 31, 2014

Seller of "Cleanse," Allergy Supplements and More Warned for Manufacturing Violations, Drug Claims

On October 15, 2014, the FDA issued a warning letter to Evangelical Christian Ministries, dba Health & Herbs, following a facility inspection which found the company's products, CORYDALIS and CVF BGONE to be adulterated because they were prepared, packed, or held under conditions that violate ...

Recalls & Warnings

April 29, 2014

Seller of B Vitamins, CoQ10, Amino Acids and Other Supplements Warned for Manufacturing Violations and Drug Claims

On April 1, 2014, the FDA issued a warning letter to Bio-Recovery, Inc.

Recalls & Warnings

April 16, 2014

Seller of Aloe, Thyroid and Other Supplements Warned for Manufacturing Violations and Drug Claims

On March 21, 2014, the FDA issued a warning letter to Aloe Man International Corp.

Recalls & Warnings

March 16, 2006

Garden of Life, Maker of Primal Defense, Settles FTC Charges

On March 9, 2006, The Federal Trade Commission (FTC) announced that an operation that marketed dietary supplements sold at Whole Foods Market, GNC, the Vitamin Shoppe, and on the Internet settled FTC charges that they made deceptive advertising claims about their supplements.

Recalls & Warnings

June 04, 2004

FTC Charges Marketers of Two Supplements with False Claims to Cure Range of Diseases

On June 3, 2004 the Federal Trade Commission (FTC) charged marketers of two dietary supplements with falsely claiming that their products can prevent and cure cancer and other diseases. According to the FTC’s complaint, Boston-area marketers Direct Marketing Concepts, Inc. (DMC), ITV Direct, Inc.

Recalls & Warnings

March 31, 2005

FDA Warns Marketer of "Vitamin O" Product to Cease Unsubstantiated Claims

The U.S. Food and Drug Adminstration (FDA) has sent a Warning Letter (dated February 8, 2005) to Donald L. Smyth, President, R-Garden Inc., and Rose Creek Health Products, Inc. warning that its "Vitamin O" product was, among other things, being marketed with unsubstantiated health claims.