Product Reviews
L-Arginine Supplements Review

Reviewed and edited by Tod Cooperman, M.D. Tod Cooperman, M.D.
Initial Posting: 8/25/17 Last Update: 10/19/19
L-Arginine Supplements Reviewed by

Choose the Best L-Arginine Supplement

Find Out Which L-Arginine Supplement Passed CL's Tests

Alphabetical list of L-arginine supplement brands compared in this review
Country Life L-Arginine Caps L-Arginine Sundown Naturals L-Arginine
Daily Wellness ArginMax - Women Purethentic Naturals Premium Arginine Swanson Super Strength L-Arginine
Elements of Health Care L-Arginine Plus - Grape Puritan's Pride L-Arginine The Vitamin Shoppe L-Arginine
GNC L-Arginine Rexall [Dollar General] L- Arginine Twinlab L-Arginine
Havasu Nutrition L-Arginine Extra Strength Solgar L-Arginine Vitacost L- Arginine HCl
MuscleTech L-Arginine SX-7 Black Onyx Spring Valley [Walmart] L- Arginine Vitamin World Maximum Strength L-Arginine
NOW L- Arginine    
Country Life L-Arginine Caps Daily Wellness ArginMax - Women Elements of Health Care L-Arginine Plus - Grape GNC L-Arginine Havasu Nutrition L-Arginine Extra Strength MuscleTech L-Arginine SX-7 Black Onyx NOW L- Arginine L-Arginine Purethentic Naturals Premium Arginine Rexall [Dollar General] L- Arginine Solgar L-Arginine Spring Valley [Walmart] L- Arginine Sundown Naturals L-Arginine Swanson Super Strength L-Arginine The Vitamin Shoppe L-Arginine Twinlab L-Arginine Vitacost L- Arginine HCl Vitamin World Maximum Strength L-Arginine
Make sure the L-arginine supplement you take passed our test and is right for you!
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  • What is it? L-arginine (or arginine) is an amino acid which is necessary for the body's production of nitric oxide, a compound that relaxes blood vessels and allows more blood to flow through arteries. The form in supplements is typically "free form" arginine, but is sometimes a compound, such as L-arginine HCl. (See What It Is). Not all labels clearly list the amount of arginine. (See What to Consider When Buying), but you can use the Results table to easily compare amounts of arginine in tested supplements.
  • What does it do? L-arginine may modestly improve symptoms, such as exercise intolerance, in congestive heart failure, angina, and leg pain due to intermittent claudication, as well as exercise endurance in recreational and older athletes. Some, but not all, studies have shown some modest benefits in sexual dysfunction and Raynaud's syndrome (See What It Does).
  • How much to take? Dosage depends on the condition being treated, but is typically several thousand milligrams per day (See Dosage).
  • Best choice? Among the products that passed our laboratory tests (See What CL Found), we selected Top Picks for arginine for general use, cardiovascular, sexual enhancement, and sport.
  • Cautions: L-arginine supplementation appears to be generally safe and well tolerated in healthy individuals, although stomach upset may occur and capsules have been reported to irritate the esophagus — so be sure to take with water. L-arginine may interact with blood-pressure lowering and diabetes medications. Do not use if you have had a heart attack, and do not use to treat serious conditions including congestive heart failure, angina, or intermittent claudication without physician supervision. For details, see Concerns and Cautions.
You must be a member to get the full test results along with's findings, recommendations, and quality ratings. You'll get results for 18 L-arginine supplements: ten selected by and eight that passed the same testing in our voluntary Quality Certification Program. There's also information about one product that is similar to one which passed testing but is sold under a different brand name.

You'll get the following information about L-arginine supplements in this comprehensive review:
    • Which L-arginine supplements passed or failed testing
    • Which L-arginine supplements are the best value and CL's Top Picks
    • What L-arginine can and cannot do for your health
    • How forms of L-arginine ("free form," L-arginine HCl, and L-arginine-alpha-ketoglutarate) differ from one another
    • The dose of L-arginine for specific uses
    • What to look for on product labels and how to take L-arginine supplements
    • Why the amino acid citrulline is often added to L-arginine supplements and whether it's been shown to help
    • Cautions, side effects, and drug interactions with L-arginine

If you already are a member, SIGN IN now.

Learn More About L-Arginine Supplements Answers -- for L-Arginine Supplements Review
I have low blood pressure. Are there any supplements I should avoid? Get the answer >>

Is L-arginine helpful or harmful for people with cancer? Get the answer >>

Which supplements help with erectile dysfunction? Get the answer >>

Have any supplements been shown to increase women's libido? Get the answer >>

Does citrulline improve exercise performance or recovery? Get the answer >>
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