Capsimax for Weight Control: Does It Work & Is It Safe?

Medically reviewed and edited by Tod Cooperman, M.D.

Written by Meredith A. Worthington, Ph.D.

Published May 07, 2026

Answer:

Capsimax by OmniActive Health Technologies is a branded cayenne pepper (Capsicum annuum) extract found in supplements promoted for weight loss, such as MST Capsimax, Burn Evolved, and Cellucor SuperHD Thermogenic Fat Burner.

Each 100 mg of Capsimax contains 2 mg of capsaicinoids (Rogers, BMC Obes 2018). As we discuss, clinical studies with Capsimax have yielded mixed results, and any potential benefit may require a dose higher than what is found in some marketed products. Safety data for Capsimax is also very limited.

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