Do plasmalogen supplements improve cognitive function and memory?

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Prevagen vs Plasmalogen

Medically reviewed and edited by Tod Cooperman, M.D.

Written by Meredith A. Worthington, Ph.D.

Updated October 10, 2024 ⓘ

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Answer:

Plasmalogens, a type of phospholipid (i.e., a compound made up of a fat and a phosphate group), are marketed as supplements to improve cognitive function and focus, support memory, and reduce brain fog, especially in older adults. While there is some preliminary evidence that plasmalogens play a role in brain function, the evidence for it being useful as a supplement for people is very limited, including a very preliminary clinical study published in 2022.

At the same time, the cost for plasmalogens is relatively high for a supplement ($2.50 or more per daily serving for products such as Daiwa Brain Health, NeuroREGAIN, ProdromeGlia, and ProdromeNeuro).

Sign in as a ConsumerLab member for details about plasmalogens, including if they are safe and effective and how much can be obtained from commonly consumed foods such as meats, poultry, fish and seafoods.

+ — 13 sources

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7 Comments

Matt21539

January 03, 2025

I’ve been taking ProdromeNeuro since it was available and hope to continue taking it as I believe that it positively affects my cognition. I have no financial stake or other interest in Prodrome.com, just a lot of gratitude.

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Charles20861

October 13, 2024

Had been buying Japanese plasmalogen tiny capsules for a very long time and had not been sure of the improvement in Brain function. It was made from squid plasmalogen. Well that has stopped as I get enough from my diet.

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Peter Rich

October 13, 2024

Just eat those foods rather than wasting money on these pills…

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Helen20834

October 11, 2024

We constantly see new substances marketed with practically no research. And with enough marketing, something like Prevagen sells. But I do find the less known citicoline worthwhile for memory and visual acuity. I personally buy the cognizin brand.

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