Product Reviews
Choline Supplements Review (Including Phosphatidylcholine, CDP-Choline, and Alpha-GPC)

Reviewed and edited by Tod Cooperman, M.D. Tod Cooperman, M.D.
 Initial Posting: 1/28/17 Last Update: 12/3/19
Choline supplements (including phosphatidylcholine, alpha-GPC, and CDP-choline) reviewed by

Choose the Best Choline Supplement

Find Out How Much Choline Popular Supplements Really Provide

Choline supplements compared in this review
Andrew Lessman ProCaps Phosphatidyl Choline Complementary Prescriptions CDP Choline Swanson Ultra Alpha-GPC
Bestvite Cognizin Jarrow Formulas Alpha GPC tnvitamins Citicoline
Biotics Research Corporation Phosphatidylcholine Perque Choline Citrate Twinlab Choline Cocktail
Cardiovascular Research Ltd. Cytidine Choline Recall Elements  
Andrew Lessman ProCaps Phosphatidyl Choline Bestvite Cognizin Biotics Research Corporation Phosphatidylcholine Cardiovascular Research Ltd. Cytidine Choline Complementary Prescriptions CDP Choline Jarrow Formulas Alpha GPC Perque Choline Citrate Recall Elements Swanson Ultra Alpha-GPC tnvitamins Citicoline Twinlab Choline Cocktail
Make sure you're choosing the best choline supplement!
Isn't your health worth it?
Choline is an unusual essential nutrient. You can get it from foods but you can also make it in your body. However, many people are not able to produce enough choline (such as postmenopausal women and people with certain genetics). Getting adequate choline from the diet helps prevent fatty liver and muscle damage which can occur with choline deficiency and, during pregnancy, may reduce the risk of birth defects. Supplemental choline has shown potential benefit with respect to stroke recovery, cognition, Alzheimer's disease, asthma, and ulcerative colitis.
A problem with choline supplements, however, is that they rarely list the amount of choline they contain. If you simply purchase a choline supplement and follow the instructions on its label, you could end up with a daily serving of choline ranging from as little as 50 mg to as much as 1,500 mg! 
To help, selected and purchased ten popular choline supplements and tested their amounts of choline. We also compared them on price — finding that you could be paying almost 10 times as much as you need to depending on the brand you choose.

Finally, identified several products which offer exceptional quality and value — making them CL's Top Picks

You must be a member to get the full test results along with recommendations and quality ratings. You will get results for 10 choline-containing supplements selected by and for a product which passed testing in our voluntary Quality Certification Program. In this comprehensive review, you'll discover:

    • Which choline supplements passed our tests and which did not
    •'s Top Picks, representing the best quality choline supplements at the best price
    • Differences among forms of choline, including phosphatidylcholine (from lecithin), CDP-choline, citicoline, Cognizin, choline citrate, Alpha-GPC, choline alfoscerate and choline bitartrate
    • The evidence behind the health benefits of choline
    • How to buy and use choline supplements
    • How to get choline from foods
    • Choline's side effects, cautions, and particular concerns with choline bitartrate

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Learn More About Choline Supplements Answers -- for Choline Supplements Review (Including Phosphatidylcholine, CDP-Choline, and Alpha-GPC)
Does Alpha Brain really improve memory, focus and cognition? Get the answer >>

Do either phosphatidylserine or phosphatidylcholine help with memory and cognition? How are these supplements different? Get the answer >>

Which supplements can cause diarrhea? Get the answer >>

Which supplements reduce the risk of stroke? Which increase the risk of stroke? Get the answer >>

Do any supplements help for ulcerative colitis? Get the answer >>

Are there vitamins or supplements that can reduce my risk of breast cancer? Do any increase cancer risk? Get the answer >>
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