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Our Members Asked:
Do supplements help with Parkinson’s disease treatment or prevention?
Answer:
There is no good evidence that dietary supplements help delay progression or improve motor impairment in people with Parkinson's disease unless they are deficient in nutrients, although some may help with non-motor symptoms, such as sleep disturbance, depression, and psychoses.
Sign in to learn what has been shown with vitamins D and E, niacin, vitamins B-6 and B-12, coenzyme Q10 (CoQ10), melatonin, creatine, S-adenosyl-L-methionine (SAMe), N-acetyl-cysteine (NAC), valerian, magnesium, curcumin, cannabidiol (CBD) and mannitol, as well as with coffee and the Mediterranean and MIND diets. Also, learn about Mucuna pruriens as a natural source of levodopa (L-dopa) and if labels on supplements are accurate.
In addition the results of its expert testing, ConsumerLab uses only high-quality, evidence based, information sources. These sources include peer-reviewed studies and information from agencies such as the FDA and USDA, and the National Academy of Medicine. On evolving topics, studies from pre-print journals may be sourced. All of our content is reviewed by medical doctors and doctoral-level experts in pharmacology, toxicology, and chemistry. We continually update and medically review our information to keep our content trustworthy, accurate, and reliable. The following sources are referenced in this article:
- Airoldi, Metabolism 1978
- Bega, J Mov Disord 2014
- Cilia, Neurology 2017
- Cohen, JAMA Neurol 2022
- Daidone, PLoS One 2012
- Hinz, Clin Pharmacol 2014
- Linetsky, Front Neurol 2022
- Metcalfe-Roach, Mov Disord 2021
- Ross, JAMA 2000
- Shaltiel-Karyo, J Biol Chem 2013
- retracted
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Related Reviews (11)
Latest Research Updates (Clinical Updates)
DopaBoost
August 01, 2024
B-6 Depleted by Parkinson’s Drug?
August 19, 2022
Can vitamin B-6 levels in the body be depleted by carbidopa, a drug taken in combination with levodopa for Parkinson's disease? Find out what evidence suggests in our updated CL Answer about supplements for Parkinson's disease.
Caution With Mucuna for Parkinson’s?
August 09, 2022
Mucuna pruriens is a natural source of levodopa (a drug for treating Parkinson’s disease). A recent study in a major journal suggested that labels for Mucuna pruriens supplements were highly misleading – however, we analyzed their data and came to a different conclusion. Learn more in our updated CL Answer about Supplements for Parkinson's Disease.
Related CL Answers (2)
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