Product Reviews and Information for Migraine
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CL Answer
Do any supplements or foods help with migraine? Do any trigger migraine?
Find out if supplements such as magnesium, CoQ10, riboflavin, butterbur, feverfew and others help with migraine. Also learn about foods that may trigger migraine, including chocolate and watermelon.
CL Answer
What are the health benefits of palmitoylethanolamide (PEA), and is it safe?
Palmitoylethanolamide (PEA) is commonly promoted for its anti-inflammatory and pain-relieving effects. Find out if it works.
Clinical Update
4/29/2022
Resveratrol for Migraine?
Can resveratrol supplementation decrease the frequency or severity of migraine in women with menstrual migraine? See what a new study showed in the What It Does section of our Resveratrol Supplements Review.
Also see our answer to the question: Do any supplements or foods help with migraine? Do any trigger migraine?
Product Review
Ginger Supplements, Chews & Spices Review
Tests Reveal Best and Worst Ginger Supplements & Spices. Poor Quality and Lead Contamination Discovered in Some Products.
Product Review
Fish Oil, Krill Oil, and Algal Oil Omega-3 (DHA & EPA) Supplements Review
See Our Omega-3 Top Picks and Avoid Rancid Fish Oils.
Product Review
Probiotic Supplements Review (Including Pet Probiotics)
Probiotics: See What They Really Contain and Our Top Picks
Product Review
Dark Chocolates, Cocoa & Cacao Powders, Nibs, and Supplements Review -- Sources of Flavanols
Is Your Chocolate or Cocoa Healthful or Toxic? Find the Best Dark Chocolate, Cocoa Powder and Cocoa Supplements Based On Our Tests.
Clinical Update
8/17/2021
Diets to Reduce Migraine?
Certain diets are associated with fewer and less severe migraine attacks, according to a recent study. Get the details in our updated answer to the question: Do any supplements or foods help with migraine? Do any trigger migraine?
Clinical Update
2/13/2024
PEA for Migraine?
Does taking PEA (palmitoylethanolamide) reduce migraine pain or lessen the number and severity of future episodes? Find out what a recent study showed in the Health effects section of our article about PEA, which includes a comparison of PEA products.
Also see: Do any supplements or foods help with migraine? Do any trigger migraine?
Clinical Update
3/21/2024
Fish Oil for Migraines?
Fish oil may reduce the frequency of migraine headache, although a recent study suggested the benefit may depend on gender. For details, see the Migraine Headache section of our Fish Oil Supplements Review, which includes our Top Picks.
Also see: Do any supplements or foods help with migraine? Do any trigger migraine?
Clinical Update
8/26/2024
Prebiotic for Migraine?
Did supplementing with inulin, a prebiotic, reduce the frequency, severity or duration of migraine in women? Find out what a recent study showed in our Prebiotics Supplements Review, which includes our Top Pick among prebiotics.
Also see: Do any supplements or foods help with migraine? Do any trigger migraine?
CL Answer
Does chocolate really cause migraines?
Find out if there is a link between chocolate/cocoa and migraines.
Product Review
Vitamin D Supplements Review (Including Calcium, Magnesium, Vitamin K, and Boron)
Find the Best Vitamin D Supplement and Avoid Problems
Product Review
CoQ10 and Ubiquinol Supplements Review
Find the Best CoQ10 and Ubiquinol Supplements and Learn How They Differ
Product Review
L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review
Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.
Clinical Update
4/27/2021
Migraine & Watermelon?
Can watermelon or other natural foods trigger migraine? See what a recent study found in our updated article about Supplements, Foods, and Migraine.
Clinical Update
7/07/2021
Fish Oil for Migraine?
Can the risk of migraine headache be reduced by increasing intake of omega-3 oils from fish? Find out what a recent study showed in the Migraine Headache section of our Fish Oil Supplements Review. Also see our Top Picks among canned tuna, salmon and sardines.
Clinical Update
8/05/2024
Magnesium for Dizziness?
Does taking magnesium reduce dizziness in people who experience vertigo with migraine (vestibular migraine)? Find out what a recent study found in the Migraine section of our Magnesium Supplements Review, which includes our Top Picks among magnesium supplements.
Clinical Update
11/05/2016
Melatonin for Migraine
Melatonin was shown to reduce migraine headaches as well as a prescription migraine drug but with fewer side-effects in a recent study. Get the details in the "What It Does" section of the Melatonin Supplements Review >>
Clinical Update
7/10/2018
CoQ10 for Migraine
CoQ10 and its active form, ubiquinol, have been studied in several clinical trials to treat migraine headache. Find out what the research is showing in the Migraine section of the CoQ10 and Ubiquinol Supplements Review. (Also see our Top Picks among CoQ10 and ubiquinol supplements.)
Clinical Update
5/01/2025
PEA for Migraine?
Did taking PEA (palmitoylethanolamide) plus melatonin reduce migraine attacks in a recent study? Find out in the Health Effects section of our article about PEA, which includes our comparison of PEA products.
Melatonin, alone, has also shown some benefit with migraine, as noted in our Melatonin Supplements Review, which includes our Top Picks for melatonin.
Clinical Update
1/16/2025
Vitamin D & Migraine
Low blood levels of vitamin D have been linked with higher migraine frequency. A new study suggests why. Get the details in our Vitamin D Supplements Review, which includes our Top Picks for vitamin D.
Also see our article about supplements and migraine.
CL Answer
Do diamine oxidase (DAO) supplements for histamine intolerance really work?
DAO supplement info for histamine intolerance, including diamine oxidase safety, evidence from clinical studies, and dosage.
Product Review
Magnesium Supplements Review (Including Calcium, Vitamins D & K, and Boron)
Find Out What Magnesium Does, Who Needs It, and Our Top Picks Among Supplements
CL Answer
Estrogen Creams for Wrinkles?
Find out if estrogen creams can help reduce wrinkles, whether they are safe, and how "prescription" estriol and estradiol creams and gels differ from those sold over-the-counter.
Product Review
Melatonin Supplements Review
Trouble Sleeping? See CL's Tests of Melatonin Supplements and Top Picks.
Product Review
Toprol XL vs. Generic Metoprolol Succinate Extended-release (ER) Tablets Review Article
Choose the Best Blood Pressure Medication. Find Out Why Some Generic Blood Pressure Medications Are Not the Same as the Original & May Increase Blood Pressure or Have Other Disturbing Side Effects.
Clinical Update
Product Review
Resveratrol Supplements Review (From Red Wine, Knotweed, and Other Sources)
See Which Resveratrol Supplements Were Best In Our Tests and Comparisons. Learn What Resveratrol Can and Can't Do.
Clinical Update
1/14/2017
Fish Oil for Migraine
Although the evidence to-date has been mixed on whether taking fish oil reduces migraine headaches, a recent placebo-controlled study showed a significant benefit for fish oil when taken along with a prescription medication. For details, see the "What It Does" section of the Fish Oil Supplements Review >>
Clinical Update
2/02/2019
A Probiotic for Migraine
Use of a particular probiotic for several weeks was found to modestly reduce the frequency and severity of migraine headaches. Get the details in the What It Does section of the Probiotic Supplements Review.
Clinical Update
1/27/2025
Do Estrogen Creams Cause Migraine?
Several CL members have reported migraine after using estrogen creams. Is this a known side effect? Find out in our article about estrogen creams for wrinkles.
CL Answer
Can biotin supplements really strengthen nails or improve hair? Can other supplements help?
Learn more about strengthening brittle nails with vitamin B-7 (biotin), based on clinical evidence.
CL Answer
Will pregnenolone help slow down aging or reduce chronic pain?
Learn more about the steroid hormone pregnenolone, including its effects in the body and on aging and chronic pain.
CL Answer
How do I choose the best magnesium supplement?
Choosing the best form of magnesium supplements can be tricky due to the many different types (magnesium aspartate, bicarbonate, carbonate, chloride, citrate and others).
Clinical Update
Clinical Update
11/27/2018
Melatonin for Headaches
Recent reports suggest that melatonin, taken daily, may eliminate episodes of stabbing headache. Melatonin may also benefit people with migraine headache. For details, see the Headache section of the Melatonin Supplements Review. (Also see our Top Picks for melatonin.)
Product Review
Prebiotic Supplements Review
You Can't Tell How Much Fiber Is Really In Most Prebiotics Without Testing
CL Answer
Are intravenous (IV) vitamin infusions safe and effective?
Intravenous (IV) vitamin infusions are touted by celebrities and promoted by wellness clinics for numerous conditions. Find out if they work and if they are safe.
CL Answer
Is sublingual vitamin B-12, which is placed under the tongue and allowed to dissolve, really better than the pill form?
Learn the difference between sublingual vitamin B-12, vitamin B-12 pills and more through information including clinical evidence.
CL Answer
Are there any supplements I should avoid when taking acetaminophen (Tylenol)?
Find out if there are any supplements that should be avoided when taking acetaminophen (Tylenol).
CL Answer
Are there drug interactions with magnesium supplements?
Find out about interactions between magnesium supplements and over-the-counter antacids and laxatives such as Maalox, antibiotics, and statins and diabetes medications. ConsumerLab’s answer explains.
Product Review
Canned Tuna, Salmon, Sardines & Mackerel Review
Find Fish With the Least Mercury & Arsenic and Most Omega-3s
CL Answer
Can any supplements be used to reduce inflammation in people sensitive to NSAIDs such as ibuprofen, high-dose aspirin, or naproxen?
Find out if supplements such as turmeric, fish oil, MSM (methylsulfonylmethane), SAMe (S-adenosyl-methionine), boswellia, ginger, white willow bark or arnica may, or may not, be helpful to people sensitive to NSAIDs.
CL Answer
Is there a risk of liver toxicity with certain supplements?
Find out if there is risk of liver damage from supplements such as green tea, niacin, red yeast rice and vitamin A.
Product Review
Glycine Supplements Review
Tests of Glycine Show High-Quality but Major Savings with Right Products.
Recalls & Warnings
February 22, 2024
Pacific BioLogic Co. Warned by FDA for Manufacturing Violations
On December 21, 2023, the FDA issued a Warning Letter to Curtis Jacquot, dba Pacific BioLogic Co.
Product Review
Cholesterol-Lowering Supplements Review (Sterols/Stanols and Policosanol)
Find the Best Cholesterol-Lowering Supplement. See Which Plant Sterol and Policosanol Supplements Passed Our Tests and Are Our Top Picks.
News Release
May 07, 2024
ConsumerLab Tests Magnesium Supplements, Spots Problems and Selects a Top Pick
White Plains, NY, May 7, 2024 — Nearly half the U.S. population does not get adequate amounts of magnesium and may benefit from increasing magnesium intake from foods or supplementation.
CL Answer
I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?
Supplement interactions with proton pump inhibitor (PPI) drugs like omeprazole (Prilosec) and Nexium.
CL Answer
What is Prelief? Does it really help for heartburn and/or bladder pain from acidic foods?
Prelief information, including what it has been claimed to do (such as helping with painful bladder, frequent urination, heartburn or indigestion from acidic foods), clinical evidence, and safety.
CL Answer
Which supplements help with Raynaud's phenomenon?
Raynaud's phenomenon may be helped by some supplements. Learn more about fish oil, Gingko biloba, and ginseng.
Product Review
B Vitamin Supplements Review (B Complexes, B6, B12, Biotin, Folate, Niacin, Riboflavin & More)
See Our Top Picks and Which 5 Failed Testing
News Release
April 11, 2024
Best CoQ10 & Ubiquinol Supplements According to ConsumerLab Tests
White Plains, NY, April 11, 2024 — CoQ10 and its active form, ubiquinol, are among the most popular supplements, taken by 42.2% of supplement users, often taken by people on cholesterol-lowering statin medication and for a variety of other conditions.
CL Answer
Does cat’s claw have any health benefits and is it safe?
Cat's claw is promoted for numerous conditions, including arthritis (including osteoarthritis and rheumatoid arthritis), Alzheimer's disease, viral infections, boosting immune response to vaccination, and reducing side effects of chemotherapy. Find out if it works and if it's safe.
Recalls & Warnings
November 29, 2019
FDA Warns Seller of "All Natural" Treatment for Opioid Withdrawal, Migraines & More
On November 18, 2019, the FDA issued a warning letter to EPH Technologies, Inc., following a review of the company's websites, which found statements made about some of the company's products, including Detoxoplex, Sinople, and Migrenz, to be drug claims.
Recalls & Warnings
November 10, 2020
FDA Warns Immusist for Drug Claims
On October 16, 2020, the FDA issued a warning letter to Immusist, LLC following a review of the company's website, which found statements made about the company's products IMMUSIST Original and IMMUSIST Natural to be drug claims.
News Release
March 11, 2022
Best Magnesium Supplements Identified by ConsumerLab
White Plains, New York, May 12, 2022 — Nearly half the U.S. population does not get adequate amounts of magnesium and can benefit from increasing magnesium intake from foods or supplementation.
News Release
September 11, 2021
Best CoQ10 and Ubiquinol Supplements Identified in Testing by ConsumerLab
White Plains, New York, September 11, 2021 — CoQ10 and ubiquinol, the active form of CoQ10, are often taken to offset a decline in natural levels that occurs with the use of statin (cholesterol-lowering) medication, and are also promoted for increasing energy and anti-aging effects.
News Release
November 12, 2019
Best Magnesium Supplements Revealed by ConsumerLab
White Plains, New York, November 12, 2019 — Many people do not get adequate amounts of magnesium from their diets, or may have lower levels of this essential mineral due to certain medical conditions or the use of common medications such as Nexium and Prilosec.
News Release
July 31, 2019
ConsumerLab Tests Reveal Best CoQ10 and Ubiquinol Supplements
White Plains, New York, July 31, 2019 — CoQ10 is among the most popular supplements, commonly taken to offset a decline in natural levels of CoQ10 that can occur with the use of statin medications, decrease statin side effects, and increase energy.
News Release
July 31, 2018
Best L-Tryptophan and 5-HTP Supplements Identified by ConsumerLab -- ConsumerLab Tests Strength and Purity of Supplements for Sleep and Mood
White Plains, New York, July 31, 2018 — L-tryptophan supplements are often promoted to improve sleep and 5-HTP supplements to help with depression.
News Release
June 21, 2017
Which Magnesium Is Best? ConsumerLab.com Tests Popular Brands and Reveals Its Top Pick
White Plains, New York, June 21, 2017 — Magnesium supplements are among the most popular supplements, but do you need to take one and, if so, which is best? To find out, ConsumerLab.com reviewed the clinical evidence, and purchased and tested popular magnesium supplements sold in the U.S.
News Release
December 21, 2016
Best CoQ10? ConsumerLab.com Tests Popular CoQ10 and Ubiquinol Supplements and Reveals Its Top Picks
White Plains, New York, December 21, 2016 — Although CoQ10 and ubiquinol are among the most popular supplements, wide variations in price, dosage, absorption and bioavailability can make choosing the right product a difficult task. To help, ConsumerLab.
Recalls & Warnings
September 08, 2020
FDA Warns Seller of Opioid Withdrawal Supplement
On August 25, 2020, the FDA issued a warning letter to Renewal Supplements LLC following a review of the company's website, which found statements made about the company product Opi-Cure to be drug claims.
Recalls & Warnings
July 31, 2020
FDA Warns Seven Sellers of "Hangover Cures"
The FDA recently issued warning letters to seven companies for promoting hangover relief products with drug claims (use the links below to read the full warning letter):
Recalls & Warnings
June 20, 2003
Mixing Herbal Supplements, Migraine Medications Can Be Dangerous
On June 19, 2003, ABC News reported than an extensive review of existing research has led University of Utah researchers to conclude several popular herbal supplements may cause adverse, even deadly, reactions when combined with certain migraine medications.
News Release
June 10, 2015
ConsumerLab.com Tests Reveal Best and Worst Magnesium Supplements
White Plains, New York, June 10, 2015 — Magnesium supplements have become extremely popular, surpassing even calcium among frequent users of supplements. However, recent tests by ConsumerLab.
News Release
March 17, 2015
CoQ10 & Ubiquinol Supplements Vary in Quality, as Well as Dose, Absorption, and Price According to ConsumerLab.com
White Plains, New York, March 17, 2015 — Findings from a recent study by ConsumerLab.com highlights the difficulty consumers have in selecting a supplement containing the highly-popular anti-oxidant CoQ10 or its activated form, ubiquinol. ConsumerLab.
Recalls & Warnings
March 09, 2022
FDA Warns Seller of Magnesium, CBD, Herbal Extracts & More
On February 9, 2022, the FDA issued a warning letter to Bea Lydecker’s Naturals, Inc.
Recalls & Warnings
September 08, 2020
Seller of "Diabetes Supplement" & More Warned for Drug Claims
On August 25, 2020, the FDA issued a warning letter to Nutritional Supplements Corporation Inc following a review of the company's website, which found statements made about some of the company's products, including Vitadone, Diabrex, and Viadevita to be drug claims.
Recalls & Warnings
April 14, 2020
Teami Tea Settles Charges of Unproven Claims and Deceptive Celebrity Endorsements
On March 6, 2020, the FTC announced that Teami, LLC, a marketer of tea and skin care products, agreed to settle charges that it was selling products with unproven claims and misleading celebrity endorsements.
Recalls & Warnings
April 02, 2019
FDA Issues Strong Warnings to Sellers of CBD
On March 28, 2019, the FDA issued warning letters to three companies for making unsubstantiated claims about the health benefits of CBD (cannabidiol) products on their websites.
Recalls & Warnings
January 05, 2005
Marketers of Brain-Rejuvinating Supplement Settle FTC Charges of False Claims
On January 5, 2005, the U.S. Federal Trade Commission (FTC) announced that a company that heavily advertised an herbal dietary supplement called "Sagee" to the Chinese-language and Vietnamese-language communities had settled FTC charges of making false and unsubstantiated claims for the product.
News Release
March 05, 2013
CoQ10 & Ubiquinol Supplements Should Be Chosen Carefully, Cautions ConsumerLab.com -- Less Than 4% of Listed Ingredient Found in Widely-Sold Product
White Plains, New York — March 5, 2013 — A new report from ConsumerLab.com highlights the difficulty consumers have in selecting a supplement containing the anti-oxidant CoQ10 or its activated form, ubiquinol. ConsumerLab.
News Release
May 30, 2012
ConsumerLab.com Identifies Best and Worst Magnesium Supplements Based on Tests and Comparisons
White Plains, New York — MAY 30, 2012 — Magnesium supplements are among the most popular supplements in the U.S. But which magnesium supplements are best? ConsumerLab.
News Release
March 08, 2011
ConsumerLab.com reviews CoQ10 and ubiquinol supplements -- Tests show quality to be high, but large differences found in dosage, formulation, and cost
WHITE PLAINS, NEW YORK — MARCH 8, 2011 — A new report by ConsumerLab.com highlights the difficulty consumers may have in selecting a supplement containing the anti-oxidant CoQ10 or its activated form, ubiquinol. CoQ10 is among the most popular dietary supplements in the U.S.
News Release
May 19, 2009
Review of Magnesium Supplements by ConsumerLab.com Shows One-Quarter Fail Quality Tests
WHITE PLAINS, NEW YORK — MAY 19, 2009 — ConsumerLab.com reported today that among twelve magnesium supplements selected for testing, only nine met quality standards. One supplement contained only 45.
News Release
January 13, 2009
ConsumerLab.com reports largest test of CoQ10 and ubiquinol supplements -- Most supplements provide claimed ingredient, but large variation in dosage and forms may confuse consumers. ConsumerLab.com provides guidance.
WHITE PLAINS, NEW YORK — JANUARY 13, 2009 — A report by ConsumerLab.com on supplements containing the anti-oxidant CoQ10 shows the difficulty for consumers in determining an appropriate dosage.
News Release
March 17, 2008
As problems surface, Consumerlab.com and the people's pharmacy ask FDA to disclose differences between generic and original drugs
WHITE PLAINS, NEW YORK AND DURHAM, NORTH CAROLINA — MARCH 17, 2008 — An investigation by ConsumerLab.
News Release
October 30, 2007
Recently tested magnesium supplements free of lead, but one product missing most of its ingredient according to ConsumerLab.com — First Major Product Review of Potential "Life-Extending" Ingredient
WHITE PLAINS, NEW YORK — OCTOBER 30, 2007 — ConsumerLab.com reported today that its tests of magnesium supplements revealed one product to contain only 46.4% of its claimed amount of the essential mineral, despite boasting a "GMP" (Good Manufacturing Practices) seal on its label.
News Release
October 20, 2006
ConsumerLab.com report on CoQ10 supplements finds quality high but large range in suggested dosage
WHITE PLAINS, NEW YORK — OCTOBER 20, 2006 — New test results from ConsumerLab.com for CoQ10 supplements show that all of the products selected contained amounts of ingredient consistent with their labels.
Recalls & Warnings
September 27, 2016
Seller of B Vitamins, Omega-3s and More Warned for Manufacturing Violations, Drug Claims
On September 15, 2016, the FDA issued a warning letter to Positive Power Nutrition, following a facility inspection which found the company's products, including High Energy C-Complex, Positive Vitality, Positive Performance, Positive CardioGuard, B-Complex 100, Positive Essentials, Positive ...
Recalls & Warnings
May 18, 2012
Caution with Butterbur Indicated by UK Warning
England's Medicines and Healthcare Products Regulatory Agency (MHRA) advised consumers in early 2012 not to take unlicensed butterbur (Petasites hybridus) herbal products due to potential health risks.
News Release
June 15, 2005
Two magnesium supplements fail testing due to lead contamination. Nineteen others pass. Report now available.
WHITE PLAINS, NY — JUNE 15, 2005 — ConsumerLab.com has released its latest report on the quality of magnesium supplements sold in the U.S. In addition to being an essential mineral, magnesium may help prevent migraine headaches, menstrual pain, PMS, and leg cramps during pregnancy.
News Release
March 30, 2005
ConsumerLab.com finds most B-vitamins of high quality but three lacking in ingredients — Test Results for 41 Products Reported Along with Information on Use
WHITE PLAINS, NY — MARCH 30, 2005 — ConsumerLab.com reported test results today for B vitamin supplements that it recently purchased in the U.S. and Canada.
Recalls & Warnings
September 05, 2014
Seller of "Nerve", "Cleanse" and Probiotic Supplements Warned for Drug Claims
On July 30, 2014, the FDA issued a warning letter to Plexus Worldwide, Inc., following a review of the company's website and product labels, which found statements made about Fast Relief, BioCleanse and ProBio5 to be drug claims.
Recalls & Warnings
May 10, 2013
Maker of Concentration, Pain, Immune, Cholesterol Supplements Warned For Drug Claims
On April 24, 2013, the FDA issued a warning letter to EuroPharma Co., Inc., following a review of the company's website which found statements made about Calm Kids, CholestCaps, CuraMed 375 mg, CuraMed 750 mg, Curamin, Mental Advantage, Tri-Iodine, and Viragen to be drug claims.
Recalls & Warnings
December 16, 2015
Maker of Red Yeast Rice, St. John's Wort, Valerian and More Warned for Manufacturing Violations, Drug Claims
On December 2, 2015, the FDA issued a warning letter to Nature's Health, LLC, following a facility inspection which found the company's product, including Ginkgo & Rhodiola, Blood Sugar Balance IV, Cinnamon Extract, Choles-Balance Red Yeast Extract, Lecithin, Milk Thistle Seed Extract, ...
Recalls & Warnings
December 21, 2016
Seller of 5-HTP, Chromium, Curcumin and More Warned for Drug Claims
On December 1, 2016, the FDA issued a warning letter to Aurora Health and Nutrition following a review of the company's website, which found statements made about its products, 5-HTP, Alpha Lipoic Acid, the Argentyn 23 product line, Artecin 90 Vegetarian Capsules, ...
Recalls & Warnings
October 21, 2014
Seller of Weight Loss, Saw Palmetto Supplements and More Warned for Drug Claims
On October 9, 2014, the FDA issued a warning letter to Bethel Nutritional Consulting, Inc., following a review of the company's website which found statements made about 15 Day Detox Diet, Alpha Lipoic Acid. 300 mg.
