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CoQ10 and Ubiquinol Supplements Review
Initial Posting: 7/19/19    Last Update: 3/21/20
Find the Best CoQ10 and Ubiquinol
See Which CoQ10 and Ubiquinol Supplements Passed or Failed Our Tests and Which Are Top Picks
Alphabetical list of CoQ10 and ubiquinol supplements compared in this review
21st Century CoQ-10
Jarrow Formulas QH-absorb + PQQ
Kirkland Signature [Costco] CoQ10
Q10 for Pets - Unflavored Pure CoQ10
BulkSupplements.com Coenzyme Q10
Life Extension Super Ubiquinol CoQ10
CVS Health CoQ-10
Member's Mark [Sam's Club] CoQ-10
Doctor's Best High Absorption CoQ10
GNC CoQ-10 400 mg
Natural Factors Ubiquinol
Qunol Mega CoQ10 Ubiquinol
Nature's Bounty Co Q-10 200 mg
Spring Valley [Walmart] CoQ10 - Natural Flavors
Healthy Origins Natural Ubiquinol
NOW Ubiquinol CoQH-CF
Swanson Q-Gel Mega
Igennus VESIsorb Ubiquinol-QH
Nutrilite Heart Health CoQ10
USANA Coquinone 30
Make sure the CoQ10 or ubiquinol supplement you take passed our test and is right for you!
Isn't your health worth it?
What does it do? People often take CoQ10 to offset a decline in natural levels which occurs with the use of statin (cholesterol-lowering) medication. Some take it to feel more energized or for a variety of other purposes. It may also modestly help with elevated cholesterol levels, migraine, and other conditions. The evidence supporting these uses remains preliminary, although it does benefit people with congestive heart failure (see What It Does). After being absorbed into the body, more than 90% of CoQ10 is converted to its active form, known as ubiquinol (CoQH2-10), which is also available as a supplement and appears to have greater bioavailability (i.e., it raises blood levels more) (see What It Is).
How much to take? CoQ10 and ubiquinol are typically taken at a dose of 50 to 200 mg per day, although higher doses have been used (see
What did CL's tests show? In laboratory testing, one product was Not Approved, as it contained nearly twice its listed amount of CoQ10. Cost comparisons showed you could spend as little as 7 cents to over $2 for an equivalent amount of CoQ10, and from 34 cents to over $1 for ubiquinol (See What CL Found).
Best choice? Among 26 CL Approved products, CL selected several Top Picks for providing high quality CoQ10 or ubiquinol at very good value.
How to take it? Gastrointestinal side-effects may occur but can be minimized by breaking up the dose throughout the day, although it may interfere with sleep if taken before bed. CoQ10 and ubiquinol are best absorbed when taken with or shortly after a fatty meal, although certain forms can be taken without fats (see Absorption and Bioavailability Enhancers).
Cautions: At typical doses, CoQ10 and ubiquinol appear to be generally safe, but there are possible interactions with blood thinners and diabetes medications (see Concerns and Cautions).
You must be a member to get the full test results along with ConsumerLab.com's recommendations and quality ratings. You will get results for 18 CoQ10 and ubiquinol supplements selected by ConsumerLab.com and 9 others which passed testing in its voluntary Quality Certification Program.
In this comprehensive review, you'll discover:
Which CoQ10 and ubiquinol supplements failed testing and which passed
CL's Top Picks, representing the best CoQ10 and ubiquinol supplements at lowest cost
Which supplements have special ingredients which may increase their absorption (such as polysorbate 80) and/or bioavailability (such as black pepper extract) — and the pros and cons of these formulas
CoQ10 and ubiquinol dosing for treating specific conditions
How to take CoQ10 and ubiquinol to reduce side-effects and enhance absorption
CoQ10 side-effects, drug interactions, and cautions
Question: I take a supplement containing a "proprietary formula" which lists many ingredients. Can ConsumerLab test the contents so I'll know the amounts of each ingredient? Get the answer >>
Question: Are CoQ10 and ubiquinol safe to take for a long period of time? Should I give it a rest period? Get the answer >>
Question: Are there negative interactions between the following supplements I take twice each day, as well as 60 mg of beta-sitosterol with dinner: Vitamin C (500 mg), CoQ10 (100 mg), grape seed extract (100 mg), fish oil (500 mg), vitamin D3/calcium/magnesium/zinc (200 IU/333 mg/113 mg/5mg)? Get the answer >>
Question: Does CoQ10 reduce wrinkles, increase skin elasticity, or tighten the skin? Are there any other supplements that can help? Get the answer >>
Question: Is it safe to take Bioperine (which contains piperine from black pepper)? Get the answer >>
Question: What is "nano" CoQ10? Is it better than other CoQ10 formulations? Get the answer >>
Question: Which supplements can help lower or control my blood sugar? Get the answer >>
Question: Can I take CoQ10 at the same time as my statin, or should I take them separately? Get the answer >>
Question: I've heard it's best to take fat-soluble supplements, like CoQ10, curcumin, and vitamin D, with fats or oils to increase absorption. Would taking them with a fish oil capsule be enough? Get the answer >>
Question: Which supplements help to improve energy and decrease fatigue? Get the answer >>
Question: Can taking CoQ10 affect my thyroid levels or interact with my thyroid medication? Get the answer >>
Question: Can CoQ10 or ubiquinol be ruined by heat? I recently purchased several bottles of Qunol Plus from Costco.com and they arrived hot. The soft gels are not melted, but I am concerned. Get the answer >>
Question: I recently bought a CoQ10 supplement on Amazon. The manufacture date was hidden under a sticker, but was 13 months ago. No "Best By" date is listed. Is this product still good to use?
Get the answer >>