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Melatonin Supplements Reviewed by


  • Does melatonin work? Melatonin supplements can help you fall asleep when taken before bedtime (30 to 60 minutes before for regular pills; 20 minutes before for fast-dissolve pills, chewables, and liquids and chewables). Melatonin may also alleviate certain types of stomach pain and reduce anxiety associated with medical procedures (see What It Does).
  • How much melatonin to take: Melatonin is a hormone; use it only as needed, not every night. Try the lowest dose that will work for you, starting with about 1 mg or less. If that doesn't work, try 3 mg. Some products contain greater amounts, such as 5 or 10 mg, which may be more than you need and can leave you groggy and have other negative effects. Timed release products may help you not just fall asleep but also stay asleep, but they won't help you stay asleep as well as a prescription sleep medication (see ConsumerTips: What to Consider When Using).
  • What did CL's tests of melatonin supplements show? In laboratory testing, one melatonin supplement was Not Approved, as it contained nearly twice its listed amount of melatonin. Our cost comparisons showed you could spend as little as 1 cent to over $5 per milligram of melatonin -- and the product that failed was among the more expensive products. (see What CL Found).
  • Best melatonin supplements? Among 22 CL Approved products, CL selected Top Picks for low, moderate, high-dose and timed release melatonin, as well as a product for pets. These products represent superior quality and value.
  • Melatonin safety and side effects: Short-term use of melatonin supplements appears to be generally safe for adults. However, melatonin can potentially affect blood pressure as well as testosterone and estrogen levels. Melatonin can also interact with certain foods and medications. Long-term use is associated with an increased risk of bone fracture. It is probably best to use melatonin "as needed" rather than on a regular basis (see Concerns and Cautions).

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Melatonin supplement brands compared in this review

View Larger Image 7040_large_Carlson-Melatonin-2020.png

Carlson Melatonin Gummies 2.5 mg - Natural Strawberry Flavor

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CVS Health Melatonin 5 mg

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GNC Melatonin 3 mg

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GNC Melatonin 5 mg

View Larger Image Herbatonin-Melatonin-Small-2017.jpg


View Larger Image 7032_large_K9Choice-Melatonin-2020.png

K9 Choice Melatonin - Peanut Butter Flavored Tabs

View Larger Image LifeExtension-3mg-Melatonin-Small-2017.jpg

Life Extension Melatonin 3 mg

View Larger Image 7044_large_MacAndMaya_Melatonin_2020.png

Mac + Maya Calming Aid With Melatonin

View Larger Image 7046_large_Natrol-Melatonin-2020.png

Natrol Melatonin 5 mg

View Larger Image 7045_large_NatureMade-Melatonin-2020.png

Nature Made Melatonin Gummies 2.5 mg - Dreamy Strawberry

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Nature's Bounty Melatonin 10 mg

View Larger Image NOW-Melatonin-Small-2017.jpg

NOW Liquid Melatonin

View Larger Image 7039_large_PuritansPride_2.5mg_Melatonin_2020.png

Puritan's Pride Melatonin 2.5 mg - Natural Strawberry Flavor

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Puritan's Pride Melatonin Liquid - Natural Black Cherry Flavor

View Larger Image 7030_large_REMfresh-Melatonin-2020.png

REMfresh Advanced Ion-Powered Melatonin

View Larger Image 7043_large_Solgar-Melatonin-2020.png

Solgar Melatonin 3 mg

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Source Naturals Melatonin

View Larger Image 7034_large_SpringValley-Melatonin-2020.png

Spring Valley Melatonin 5 mg - Artificial Strawberry Flavor

View Larger Image 7029_large_Sundown_Melatonin_2020.png

Sundown Melatonin 300 mcg

View Larger Image Swanson-Melatonin-Small-2017.jpg

Swanson Melatonin

View Larger Image 7033_large_TraderJoes-Melatonin-2020.png

Trader Joe's Chewable Melatonin 3 mg - Peppermint Flavor

View Larger Image 7038_large_USANA-Melatonin-2020.png

USANA Pure Rest

View Larger Image 7031_large_Zarbees-Melatonin-2020.png

Zarbee's Naturals Children's Sleep With Melatonin - Natural Berry Flavor

You must be a member to get the full test results along with's recommendations and quality ratings. You will get results for 13 melatonin supplements selected by and 10 others that passed testing in its voluntary Quality Certification Program. In this comprehensive review, you'll discover:
  • Which melatonin supplements passed or failed testing, and which are's Top Picks
  • How melatonin supplements compare on quality, ingredients, and cost
  • How you can potentially save hundreds of dollars per year on a supplement while getting the same amount of melatonin
  • What melatonin can and cannot do for your health
  • The differences between regular and timed release melatonin supplements
  • How natural, synthetic, and plant-based melatonin differ
  • Melatonin dosage for different sleep issues and conditions
  • Concerns, drug interactions, and potential side-effects of melatonin

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