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CL Answers (35)

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Clinical Updates (41)

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6/02/2013

Glucosamine May Increase Eye Pressure

New research suggests that people with glaucoma or intraocular hypertension could have worsening eye pressure if they take a glucosamine supplement. Get the details (along with our tests of glucosamine and other joint health supplements) in the updated Glucosamine/Joint Health Supplements Review >>
6/13/2014

Contaminated Chondroitin

A chondroitin ingredient on the market has been found to be contaminated with an inexpensive industrial compound. Get the details, along with our tests and comparisons of glucosamine and chondroitin supplements for joint health, in the update to the Review of Glucosamine, Chondroitin, MSM and Boswellia Supplements for Joint Health>> 
3/09/2019

Boswellia for Osteoarthritis

Boswellia extract may reduce the pain and stiffness of knee osteoarthritis. See results of a recent study in the What It Does section of the Joint Health Supplements Review. Also see our Top Picks for Boswellia and other joint health supplements.
5/15/2019

Glucosamine and Heart Disease

Does taking glucosamine affect your risk of developing cardiovascular disease? See what a large study recently found in the What It Does section of the Joint Health Supplements Review (Glucosamine, Chondroitin, MSM and Boswellia). Also see our Top Picks among joint health supplements.
8/30/2019

Glucosamine for Hand Osteoarthritis?

A new study suggests that glucosamine may help people with hand osteoarthritis. Get the details in the What It Does section of the Joint Health Supplements Review. Also see our Top Picks for joint health supplements.
3/03/2020

Do Glucosamine & Chondroitin Work?

After reviewing the clinical literature regarding glucosamine and chondroitin for osteoarthritis, an expert group drew conclusions regarding their efficacy. Find out what they concluded in the What It Does section of the Joint Health Supplements Review. Also see our Top Picks for glucosamine, chondroitin and other joint health supplements.
3/01/2022

Glucosamine and Depression

Can taking glucosamine improve, or cause, depression? Find out in the Glucosamine and Chondroitin section of our Joint Health Supplements Review. Also see our Top Picks among joint health supplements.

Also see our answer to the question: What are the best supplements for depression and anxiety?

9/07/2019

Vegetarian Chondroitin for Knee Pain?

Can "vegetarian" chondroitin reduce knee pain and improve mobility? See what a recent study found in the What It Does section of the Joint Health Supplements Review. Also see our Top Picks for glucosamine and chondroitin supplements.
12/07/2019

Glucosamine & Chondroitin – How They May Work

A recent study suggests that one way glucosamine and chondroitin may work is through the gut. For details, see the What It Does section of the Joint Health Supplements Review (Glucosamine, Chondroitin, MSM and Boswellia). Also see our Top Picks among products.
2/08/2020

Glucosamine and Blood Sugar

Glucosamine (used to treat osteoarthritis) is a type of sugar, so does its daily use affect blood sugar levels and one's risk of developing diabetes? Find out in the Concerns and Cautions section of the Joint Health Review. Also see our Top Picks for Glucosamine, Chondroitin, MSM, and Boswellia supplements.
7/23/2017

Does MSM Help Joints and Muscles?

MSM (methylsulfonylmethane) is commonly in supplements for joint and muscle pain, although the evidence behind it has been limited. Its effectiveness in reducing pain, muscle damage, and oxidative stress was recently evaluated in people running a half-marathon. See the results in the "What It Does" section of the Joint Health Supplements Review (Glucosamine, Chondroitin, MSM, and Boswellia), which includes our Top Picks among products.
5/28/2019

Glucosamine & Eye Pressure

Glucosamine may increase eye pressure in people with glaucoma or intraocular hypertension. But does it have this effect in people who don't have these conditions? See what a new study found in the Concerns and Cautions section of the Joint Health Supplements Review. Also see our Top Picks for glucosamine and chondroitin.
4/26/2016

Knee Supplements Studied

A recent clinical trial evaluated glucosamine with chondroitin versus placebo for reducing pain and improving function in people with osteoarthritis of the knee. See the details, along with results of our tests of popular supplements, see our Review of Glucosamine, Chondroitin, MSM and Boswellia Supplements for Joint Health >>
1/09/2018

Curcumin for Knee Osteoarthritis

A type of curcumin that has been Approved for Quality by ConsumerLab.com was found to be modestly effective in treating symptoms of knee osteoarthritis in a recently published study. For details see the Osteoarthritis section of the Turmeric & Curcumin Supplements Review.  

The same study found that combining curcumin with boswellia may be advantageous. Learn more about this and other popular supplements for joint health in the Joint Supplements Review >>
9/25/2011

Chondroitin Improves Hand Arthritis

Do you or someone you know have osteoarthritis of the hand? A new study found that highly purified chondroitin can reduce pain and stiffness and increase function. You need to give it some time, though. Get the details in the update in the Joint Health Supplements ReviewMore >>
2/23/2022

Boswellia for Knee Pain?

Can Boswellia extract reduce knee pain and stiffness in people with knee osteoarthritis? See what a recent study found in the What It Does section of our Joint Health Supplements Review. Also see our Top Picks among products containing Boswellia, glucosamine, chondroitin, and/or MSM.

See our answer to the question: Which supplements can help with arthritis?

6/10/2022

Top Pick for Boswellia (Anti-Inflammatory)

We just tested two Boswellia extract supplements (containing the anti-inflammatory compound AKBA). One failed testing but the other passed and is now our Top Pick for Boswellia. The results are in our Joint Health Supplements Review, which include our tests of supplements with glucosamine, chondroitin, MSM and other ingredients.

3/08/2014

Glucosamine & Chondroitin Help Maintain Knee Joint

A 2-year study in people with osteoarthritis of the knee found that those who took a combination of glucosamine and chondroitin had only half the amount of narrowing of the knee joint space as those who took placebo. This beneficial finding differs from that of another large study published several years ago which did not find a benefit on joint space. The new study used a different form of glucosamine than the previous study. Get the details, as well as our tests of supplements with these ingredients, in the updated Joint Health Supplements Review (Glucosamine, Chondroitin, MSM and Boswellia) >>   
7/24/2021

Collagen for Joint Pain?

Can collagen supplementation reduce joint pain or stiffness in the knee, hip or wrist? See what a new study found in the Joint Pain section of our Collagen Supplements Review. Also see our Top Picks among collagen supplements for joints and for skin.
8/14/2020

Eggshell Membrane + Fish Oil for Joint Pain?

Both eggshell membrane and fish oil have been shown to bring modest reduction in joint pain, but does taking these ingredients together have greater benefit? Find out what a new study showed in the What It Does section of the Collagen Supplements Review. Also see our Top Pick among collagen supplements for joints and for skin.
12/07/2019

Eggshell Membrane for Joints?

Eggshell membrane hydrolysates, which naturally contain collagen, have been used in clinical studies to treat joint pain. Find out if they work in the Joint section of the Collagen Supplements Review. Also see our Top Picks for collagen.
3/29/2022

Collagen for Joint Discomfort?

Can supplementing with low-dose collagen reduce joint pain in healthy older adults? Find out what a recent study showed in the Joint Pain section of our Collagen Supplements Review. Also see our Top Picks for collagen.

5/04/2021

PEA for Joint Pain?

Can PEA (palmitoylethanolamide) reduce joint pain? Find out what a recent study found in our answer to the question: Which supplements can help with arthritis?
2/01/2020

Collagen for Knees?

Collagen supplements have been tested in many studies to reduce pain and/or improve function in osteoarthritic knees. A recent study focused on collagen peptides. Find out if they worked (and see the results for other collagen products) in the Joint Pain section of the Collagen Supplements Review. Also see our Top Picks for collagen supplements for joint pain and for wrinkles.
3/31/2022

Doctor's Best Settlement & Refund

Doctor's Best is providing a partial refund to customers of its glucosamine supplements as part of a legal settlement. For details, see the Update to our Joint Supplements Review.
6/07/2022

Eggshell Membrane for Osteoarthritis?

Eggshell membrane – a source of collagen – may reduce pain in people with osteoarthritis if taken at a certain dose, according to a recent study. Get the details in the Joint Pain section of our Collagen Supplements Review.

9/19/2021

For Knee Pain, Try This.

A six-month exercise program was shown to reduce knee pain in 72% of people with osteoarthritis. It’s a completely free program that anyone can do from home. Get the details in the ConsumerTips section of our Joint Supplements Review (although no supplements are involved in the program).
10/19/2021

Alpha Lipoic Acid for Pain?

Can taking alpha-lipoic acid decrease nerve, muscle or joint pain? See what a new study found in the What It Does section of our Alpha Lipoic Acid Review. Also see our Top Picks for alpha-lipoic acid.
4/20/2021

Probiotic for Rheumatoid Arthritis?

Can taking a probiotic reduce joint swelling in rheumatoid arthritis? See what a new study found in the What It Does section of our Probiotic Supplements Review.
6/28/2021

Hyaluronic Acid for Wrinkles?

Does supplementing with hyaluronic acid reduce wrinkles or improve skin elasticity in middle-aged men and women? See what a new study found in the Aging Skin and Wrinkles section of our Collagen Supplements Review. Also see our Top Picks for collagen supplements for skin and for joints.
3/08/2016

Knee Arthritis & Vitamin D

People with knee osteoarthritis (worn joints) and generally low vitamin D levels given vitamin D for 2 years showed greater improvement in some, but not all, symptoms compared to those given a placebo. Get the details (as well as our product test results) in the Vitamin D Supplements Review >>
7/28/2020

Fish Oil for Arthritis?

Fish oil has shown modest benefits in rheumatoid arthritis, but can it help with osteoarthritis -- inflammation due to worn joints? Find out what a recently published study showed in the What It Does section of the Fish Oil Supplements Review. Also see our Top Picks for fish oil.
6/27/2020

Fish Collagen Allergy

Be aware that some people may be allergic to fish collagen even if they don't respond to common fish allergy tests, according to a recent study. Get the details in the Concerns and Cautions section of the Collagen Supplements Review. Also see our Top Picks for collagen supplements for skin and for joints.
6/07/2017

Chondroitin Matches Celebrex for Knee Pain

A type of chondroitin was found to reduce the pain of knee osteoarthritis as much as the drug Celebrex, although not as quickly. Due to potential side-effects with Celebrex, the researchers suggested that this form of chondroitin be considered a first-line therapy for knee osteoarthritis. For details, including dosage, see the "What It Does" section of the Joint Supplements Review (Glucosamine, Chondroitin, MSM, and Boswellia), which includes CL's tests and comparisons of products.
8/11/2018

CBD for Dogs

Can CBD help dogs with osteoarthritis (worn joints)? Learn what a recent study found (as well as the dose used and a potential side effect) in the CBD for Pets section of the CBD & Hemp Supplements Review. (Also see our Top Picks for CBD for pets – as well as for people).
5/05/2020

CBD for Osteoarthritis Pain

A recent study, conducted in dogs, showed promise for CBD in reducing pain and inflammation due to osteoarthritis (pain due to worn joints). See the details in the What It Does section of the CBD and Hemp Extracts Review. Also see our Top Picks for CBD for people and for pets.
12/15/2018

Pycnogenol for Prostate?

Pycnogenol, a branded form of pine bark extract, is promoted for a variety of uses, including improvement of circulation, cognition, joint pain and vision. It was recently given to men with benign prostatic hyperplasia (BPH) to see if it would improve urinary symptoms. Find out if it worked, and learn if it helps with other conditions, in our updated answer to the question: What is Pycnogenol and does it work? >>
5/15/2018

Fish Oil for Joints

See what happened when high-dose fish oil was given for a year to older men and women in the Arthritis and Other Inflammatory Diseases section of the Fish Oil Supplements Review. Also see our Top Picks among fish oils and other omega-3 supplements.
7/16/2019

Has UC-II Collagen Changed?

UC-II is an undenatured collagen that may reduce knee pain. However, one of the more recent studies reported that it contained much less collagen than reported in earlier studies. Has UC-II changed? Find out in our updated answer to the question: What is UC-II and does it help joints?
10/11/2019

Eggshell Membrane for Bad Knees?

Eggshell membrane, which naturally contains collagen, was tested as a supplement to improve knee pain, stiffness, and function. Find out if it worked in the Joint Pain section of the Collagen Supplements Review. Also see our Top Picks for collagen.
1/13/2013

Vitamin D and Knee Arthritis?

Can taking vitamin D reduce the pain and progression of osteoarthritis of the knee? A new study found no benefit for people who already had sufficient levels of vitamin D. In fact, these people needed more anti-inflammatory medication during the study than those given placebo. However, as seen in many other studies of vitamin D, people who entered the study deficient in vitamin D appeared to benefit from being given vitamin D, experiencing reduced pain. For more details, see the update in the Vitamin D Supplements Review, which includes our tests of vitamin D supplements. If you suffer from osteoarthritis of the knee or other joints, also read about glucosamine and chondroitin, as supplements with these ingredients may help. We have tested many of these products.

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