Initial Posting: 1/30/2018    Last Update: 1/30/2018
Answer: Turmeric/curcumin supplements are generally safe, but gastrointestinal side effects may occur with higher doses and they can cause problems for people with gallbladder disease or kidney stones. They can also interact with medications, such as those for blood-thinning, blood-sugar-lowering, and immunosuppression, as well as the anti-cancer drug tamoxifen. Curcumin may also inhibit iron absorption. Be aware that black pepper extract (piperine) often added to curcumin to increase bioavailability also interacts with a number of medications.
Although rare, elevated liver enzymes and liver injury have been reported with the use of turmeric/curcumin supplements.