Natural and Alternative Treatments

Vitamin K - HealthLibrary

Print PDF | Print

Natural and Alternative Treatments Index Page | Herbs & Supplements:

Vitamin K


Supplement Forms/Alternate Names
  • Vitamin K1 (phylloquinone), vitamin K2 (menaquinone), vitamin K3 (menadione)

 

Introduction

Vitamin K is found in leafy greens, whole wheat, and oats. The body needs it for blood clotting and blood flow. Vitamin K has been used to clot blood and improve bone strength.

It can be taken as a pill or powder. It can also be injected into the bloodstream or muscle by a healthcare provider.

Dosages

1 to 2 milligrams daily

 

What Research Shows

Unlikely to Be Effective

Not Enough Data to Assess

Editorial process and description of evidence categories can be found at EBSCO NAT Editorial Process.

 

Safety Notes

It is likely safe to take vitamin K in small doses for a short time. Not enough studies have been done to say whether it is safe to use for a long period.

Interactions

Talk to your doctor about any supplements or therapy you would like to use. Some can interfere with treatment or make conditions worse, such as:

  • People taking blood thinners should talk to their doctors before taking vitamin K. It may interfere with the medicine.

References [ + ]

A. Blood Clots

A1. Lam J, Schulman S, et al. Anticoagulation control with daily low-dose vitamin k to reduce clinically adverse outcomes and international normalized ratio variability: a systematic review and meta-analysis. Pharmacotherapy. 2013 Nov;33(11):1184-1190.

A2. Mahtani KR, Heneghan CJ, et al. Vitamin K for improved anticoagulation in patients receiving warfarin. Cochrane Database Syst Rev. 2014;(5):CD009917.

B. Bone Strength

B1. Cockayne S, Adamson J, et al. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med. 2006;166(12):1256-1261.

B2. Knapen MH, Schurgers LJ, et al. Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007;18(7):963-972.

B3. Iwamoto J, Sato Y, et al. High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature. Nutr Res. 2009 Apr;29(4):221-228.

B4. Stevenson M, Lloyd-Jones M, et al. Vitamin K to prevent fractures in older women: systematic review and economic evaluation. Health Technol Assess. 2009;13(45):iii-xi.

C. Cardiometabolic Risk Factors

C1. Verma H, Garg R. Effect of Vitamin K Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Endocr Metab Immune Disord Drug Targets. 2019;19(1):13-25.

D. Cardiovascular Disease

D1. Hartley L, Clar C, et al. Vitamin K for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2015;(9):CD011148.

E. Cystic Fibrosis

E1. Jagannath VA, Fedorowicz Z, et al. Vitamin K supplementation for cystic fibrosis. Cochrane Database Syst Rev. 2011;(1):CD008482.

E2. Jagannath VA, Thaker V, et al. Vitamin K supplementation for cystic fibrosis. Cochrane Database Syst Rev. 2017 Aug 22;8:CD008482.

F. Osteoporosis

F1. Fang Y, Hu C, et al. Effect of vitamin K on bone mineral density: a meta-analysis of randomized controlled trials. J Bone Miner Metab. 2012 Jan;30(1):60-68.

F2. Huang ZB, Wan SL, et al. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-1186.



Last reviewed July 2019 by EBSCO NAT Review Board Eric Hurwitz, DC
Last Updated: 3/27/2020

Back to Top


Search the Natural and Alternative Treatments Encyclopedia:

In:

 

 

   BECOME A MEMBER
JOIN NOW

SPECIAL
Coronavirus Information Center
Coronavirus Information Center
Answers to Critical Questions About COVID-19.



 
 
Join |  Sign In
   
Join Us on Facebook! Join Us on Instagram! Join Us on Twitter! Join Us on YouTube! Join Us on YouTube!
Product Reviews
Brands Tested
Health Conditions
Encyclopedia
CL Answers
Clinical Updates
News
Recalls & Warnings
Recommended Intakes
Where to Buy Products
Testing Program
How Products Were Tested
Quality Certification Program
Join CL Today
Testimonials
Join Free Newsletter
Group Subscriptions
Gift Membership
About Us
The CL Seal
CL Survey
Privacy Policy
Sitemap
Contact Us/Help

©2020 ConsumerLab.com, LLC. All rights reserved. A single copy of a report may be printed for personal use by the subscriber. It is otherwise unlawful to print, download, store or distribute content from this site without permission.
ConsumerLab.com name and flask logo are both registered trademarks of ConsumerLab.com, LLC. This site is intended for informational purposes only and not to provide medical advice.