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CL Answer
Do any supplements help reduce the symptoms of premenstrual syndrome (PMS)?
Find out which supplements help reduce premenstrual syndrome (PMS) symptoms, such as mood swings, pain, bloating, irritability and food cravings.
CL Answer
Will pregnenolone help slow down aging or reduce chronic pain?
Learn more about the steroid hormone pregnenolone, including its effects in the body and on aging and chronic pain.
Clinical Update
3/31/2013
More Iron, Less PMS?
A new study showed that women getting more iron had a significantly lower risk of suffering PMS (premenstrual syndrome) -- but not just any type of iron. Get the details, as well as our ratings of iron supplements, in the updated Iron Supplements Review »
Clinical Update
1/23/2016
Vitamin D Reduces PMS Symptoms
A recent study found that taking vitamin D significantly improved symptoms of premenstrual syndrome (PMS) in young women who were deficient in vitamin D. Get the details in the Vitamin D Supplements Review >>
Product Review
Potassium Supplements Review
Be Careful with Potassium Supplements! Problems Found. Tests and Reviews of Potassium Supplements & CL's Top Picks.
Product Review
Vitamin D Supplements Review (Including Calcium, Magnesium, Boron, and Vitamin K)
Find the Best Vitamin D Supplement with the Right Dose
Product Review
Ginkgo (Ginkgo Biloba) Supplements Review
Choose the Best Ginkgo Biloba Supplement. Finding Real Ginkgo Isn't Easy — 60% Fail ConsumerLab's Tests of Quality.
Product Review
Iron Supplements Review (Iron Pills, Liquids and Chews)
See Which Iron Supplements Are CL's Top Picks for Different Needs
CL Answer
Do any supplements help for restless legs syndrome?
Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS). ConsumerLab.com's answer explains.
CL Answer
I have IBS and don't want to take medication if I can help it. I've heard that peppermint works for IBS, but is there good research to support this?
Information about using peppermint oil for irritable bowel syndrome (IBS), including clinical evidence, dosage, safety and more.
Product Review
L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review
Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.
CL Answer
Are There Supplements That Help Treat POTS (Postural Orthostatic Tachycardia Syndrome)?
Find out which supplements and lifestyle changes may be helpful for people with Postural Orthostatic Tachycardia Syndrome (POTS).
CL Answer
Has the probiotic VSL#3 been changed or discontinued? Is Visbiome a good alternative?
Find out if the probiotic formula VSL#3 has been changed and how it compares with Visbiome. ConsumerLab.com's answer explains.
CL Answer
I developed a rash soon after starting a probiotic. Is it possible to be allergic to probiotics?
Find out if probiotics can cause allergic reactions, including skin rashes, and why.
CL Answer
What are the benefits of Daily Synbiotic by Seed Health? Does it do what it claims, and is it better than other probiotics and prebiotics?
Review of Daily Synbiotic by Seed, including information about the prebiotic and probiotic strains in the supplement, and whether there is evidence of benefit for the synbiotic.
CL Answer
What is hydrogen water? Is it beneficial for alertness, athletic performance, arthritis or other conditions, and is it safe?
Find out if hydrogen water has benefits with regard to alertness, side effects of radiotherapy in cancer patients, metabolic syndrome, athletic performance, rheumatoid arthritis, liver disease, and other conditions, and learn if it is safe to use.
CL Answer
Do probiotics help with lactose intolerance?
Find out if probiotics can help with lactose intolerance. ConsumerLab's answer explains, including some foods that may cause fewer symptoms in the lactose intolerant.
CL Answer
I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
Learn about Prozac (fluoxetine) drug interactions along with other supplements and SSRIs.
CL Answer
Can a probiotic help men with prostatitis?
Learn more about prostatitis, the effects of probiotics on prostatitis, and other natural treatments.
Clinical Update
12/07/2021
Can Warm Coffee Trigger Burning Mouth Syndrome?
A member asked if anyone else had experienced "burning mouth syndrome" after drinking warm coffee. Find out if drinking coffee can trigger symptoms of this known condition in the Safety section of our updated article about Coffee and Heart Health.
Clinical Update
12/10/2021
Magnesium for Metabolic Syndrome?
Can magnesium supplementation lower blood sugar and blood pressure in people with metabolic syndrome? Learn what a new study found in the What It Does section of the Magnesium Supplements Review. Also see our Top Picks among magnesium supplements.
Clinical Update
1/11/2022
Ginkgo and Cistanche for Chronic Fatigue Syndrome?
Does supplementing with ginkgo and cistanche extracts help reduce symptoms of chronic fatigue syndrome? See what a recent study showed in our updated answer to the question: Which supplements help to improve energy and decrease fatigue?
Clinical Update
3/02/2016
Ginseng for Metabolic Syndrome?
A study in men with metabolic syndrome found no benefit on blood sugar levels from taking ginseng, but a small increase in testosterone. Get the details about this and other uses for ginseng, as well as our quality ratings in the Ginseng Supplements Review >>
Clinical Update
7/13/2018
Melatonin and Restless Legs Syndrome
Taking a melatonin supplement can help some people fall asleep, but a study suggests that it may be a problem for people with restless legs syndrome. Get the details, and learn about potential side effects of melatonin in the Concerns and Cautions section of the Melatonin Supplements Review.
Clinical Update
6/30/2013
Probiotic for Irritable Bowel Syndrome?
A popular probiotic given in a yogurt appeared to reduce symptoms in people with irritable bowel syndrome. However, people taking a yogurt without the probiotic did just as well, if not better, over time, raising doubt about the value of the probiotic. For more details, as well as test results and comparisons for 29 probiotic supplements, see the updated Probiotic Supplements Review >>
Clinical Update
6/09/2018
Magnesium & Metabolic Syndrome
A study shows that magnesium can significantly help some people suffering from metabolic syndrome (i.e., high blood sugar, high blood pressure, and related symptoms). Get the details in the What It Does section of the Magnesium Supplements Review. Also see our Top Picks among magnesium supplements.
CL Answer
Can glycine improve sleep or reduce nighttime urinary frequency?
Can glycine really help improve sleep? Lean more about glycine and its uses and benefits.
Clinical Update
8/14/2021
J&J Vaccine Blood Clot, Guillain-Barre Risk
How common are blood clots and low platelet counts or Guillain-Barre syndrome after the J&J vaccine?
Clinical Update
6/17/2022
Supplements for POTS?
People with postural orthostatic tachycardia syndrome (POTS) experience a fast heart rate, dizziness, and other symptoms when standing. Can any supplements or lifestyle changes help? Find out in our answer to the question: Are there supplements that help treat POTS?
Clinical Update
10/18/2022
Fenugreek for PCOS?
Can supplementing with fenugreek extract improve symptoms of polycystic ovarian syndrome (PCOS)? Find out what a recent study suggests in our updated article about Supplements and PCOS.
Clinical Update
6/03/2022
Digestive Enzymes for IBS?
Does taking digestive enzymes reduce symptoms of irritable bowel syndrome (IBS)? Find out in our updated Digestive Enzyme Supplements Review.
Clinical Update
10/02/2021
Human Milk Oligosaccharides (HMOs) for IBS?
Are symptoms of IBS improved with use of human milk oligosaccharides (HMOs)? Find out what research suggests in our answer to the question: Do any supplements help for irritable bowel syndrome (IBS)?
Clinical Update
8/03/2021
Vitamin D for IBS?
Can vitamin D supplementation reduce the severity of symptoms in people with irritable bowel syndrome (IBS)? See what a new study found in the What It Does section of our Vitamin D Supplements Review. Also see our Top Picks for vitamin D.
Clinical Update
8/07/2021
Peppermint Oil for IBS?
Can peppermint oil supplements improve symptoms in people with irritable bowel syndrome (IBS)? See what a new study found in our updated article about Peppermint Oil and IBS.
Clinical Update
9/29/2020
Vitamin D and PCOS
Can vitamin D improve symptoms of (polycystic ovary syndrome (PCOS)? Find out what a recent study showed in the What It Does section of Vitamin D Supplements Review. Also see our Top Picks for vitamin D.
Clinical Update
5/01/2021
Does Kefir Lower Cholesterol?
Can drinking kefir that contains probiotics, decrease LDL cholesterol or triglyceride levels in people with metabolic syndrome? See what a new study found the Cholesterol-Lowering section of our Probiotic Supplements Review. Also see our Top Picks among probiotic supplements and drinks.
Clinical Update
12/01/2018
Vitamin D for Restless Legs?
Does high-dose vitamin D help women and men with restless legs syndrome? Find out what a recent study reported in the What It Does section of the Vitamin D Supplements Review. (Also see our Top Picks for vitamin D.)
Clinical Update
9/04/2018
Glutamine for IBS?
Glutamine, an amino acid, plays a role in maintaining the digestive tract. Can taking it as a supplement help people with irritable bowel syndrome (IBS)? Find out what a recent study showed in the Glutamine section of the Muscle Enhancers Review.
Clinical Update
5/26/2017
Probiotic Reduces Depression in IBS
A probiotic significantly decreased depression in men and women with irritable bowel syndrome (IBS), according to a recent study. For details, see the "What It Does" section of the Probiotic Supplements Review >>
Clinical Update
6/12/2019
Reaction to CoQ10 and Alpha-Lipoic Acid
An autoimmune syndrome possibly caused by CoQ10 was recently reported. It is similar to rare cases caused by alpha-lipoic acid. For details see the updates to the Concerns and Cautions sections of the CoQ10 and Alpha Lipoic Acid Reviews.
Clinical Update
6/18/2019
Melatonin for PCOS?
Can melatonin help women who suffer from polycystic ovary syndrome (PCOS)? See what a recent study found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.
Clinical Update
1/20/2013
More Probiotic Concerns
According to a published case report, two women recently developed a severely debilitating condition ("eosinophilic syndrome") two to four weeks after taking what appears to be the same "new" probiotic supplement. It's not yet known if these are isolated cases or are there more to come. For more information, see the recent update to the Probiotic Supplements Review >>
Clinical Update
1/02/2011
Probiotics and Irritable Bowel Syndrome (IBS)
A recent study of children with IBS found that eight weeks of treatment with a probiotic greatly reduced the frequency and severity of abdominal pain. See the Probiotic Supplements Review for the type and dose of probiotic used and more >>
Clinical Update
8/04/2013
5-HTP Concern
Three cases of eosinophilia-myalgia syndrome (EMS) have been reported among people taking 5-HTP, a compound related to L-tryptophan. EMS is a debilitating immune condition which has occurred in people taking L-tryptophan, but there were no previous reports of it being caused by 5-HTP. Get the details in the the updated review article on L-Tryptophan and 5-HTP >>
Clinical Update
12/17/2014
Probiotic Reduces GI Pain in IBS
A yeast-based probiotic was recently shown to significantly reduce abdominal pain and discomfort among people with irritable bowel syndrome (IBS). The most notable effect occurred after 4 weeks of use. Other studies, typically using bacterial probiotics, have also shown some benefit in IBS. For details, see the Probiotic Supplements Review >>
Clinical Update
5/25/2014
Probiotic for IBS Symptoms
A recent study found that a multi-strain probiotic reduced certain symptoms of irritable bowel syndrome (IBS). Get the details, as well as our tests of probiotic products, in the updated Probiotic Supplements Review >>
Clinical Update
3/02/2016
Probiotic Helps with IBS
A probiotic was found to improve many symptoms of irritable bowel syndrome in a recent study. Studies with other probiotics have also shown benefits, but be aware that the choice of probiotic seems to depend on the type of IBS. Get the details, as well as our quality ratings, in the Probiotic Supplements Review >>
Clinical Update
10/06/2015
Probiotic Improves IBS Symptoms
A probiotic significantly improved symptoms in men and women with a particular type of irritable bowel syndrome (IBS), according to a recent study. Get the details, including dosage, and our tests of popular products, in the Probiotic Supplements Review >>
Clinical Update
5/24/2017
POTS and Thiamin
A small study among people who suffer from POTS (postural tachycardia syndrome) suggested that supplementing with thiamin (vitamin B-1) may help some. For details, see the Thiamin (B-1) section of the B Vitamin Supplements Review >>
Clinical Update
8/02/2017
Iron for Restless Legs
Iron supplementation may help to reduce the severity of restless legs syndrome (RLS) symptoms in people who have deficient or low levels of iron, according to guidelines from the American Academy of Neurology. For details, including dosage, see the "What It Does" section of the Iron Supplements Review, which also includes our tests and quality comparisons of products.
Clinical Update
2/10/2017
High-Dose Resveratrol Increases "Bad" Cholesterol
A study of middle-aged men with metabolic syndrome found that high doses of resveratrol increased levels of "bad" LDL cholesterol. Get the details in the "What It Does" section of the Resveratrol Supplements Review (which includes our tests of products) >>
Clinical Update
6/12/2018
Probiotic for IBS?
Studies have shown that certain probiotics help relieve symptoms of irritable bowel syndrome (IBS), although this can depend on the type of IBS. The most recent study focused on people with diarrhea-predominant IBS. Get the results in the What It Does section of the Probiotic Supplements Review. Also see our Top Picks among probiotics.
Recalls & Warnings
2/22/2021
FDA Warns Seller of Melatonin & Other Sleep Supplements
On February 18, 2021, the FDA issued a warning letter to SANA Group LLC following a review of the company's website, which found statements made about the company's products Sleep Sana Sleep Drops and Sleep Shots to be drug claims.
News Release
7/31/2018
Best L-Tryptophan and 5-HTP Supplements Identified by ConsumerLab -- ConsumerLab Tests Strength and Purity of Supplements for Sleep and Mood
White Plains, New York, July 31, 2018 — L-tryptophan supplements are often promoted to improve sleep and 5-HTP supplements to help with depression.
Recalls & Warnings
4/17/2020
Seller of Vitamin D, MSM, Selenium & More Warned for Drug Claims
On March 31, 2020, the FDA issued a warning letter to KetoKerri LLC following a review of the company's website, which found statements made about some of the company's products, including Dr.
Recalls & Warnings
1/17/2018
Joint and Pain Relief Product Contains Undeclared Drug
On January 17, 2018 Health Canada warned consumers that Linsen Double Caulis Plus, a supplement for joint pain, was found to contain the undeclared drug dexamethasone.
Recalls & Warnings
9/13/2013
Metagenics Warned For Misbranding of Medical Foods and Drug Claims
On August 13, 2013, the FDA issued a warning letter to Metagenics, Inc.
Recalls & Warnings
12/21/2012
Dangerous Supplement Being Sold Under New Name
On December 21, 2012, the FDA warned consumers that Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain that has been linked to serious and sometimes fatal side effects, is now being sold under the name WOW.
Recalls & Warnings
3/16/2006
Garden of Life, Maker of Primal Defense, Settles FTC Charges
On March 9, 2006, The Federal Trade Commission (FTC) announced that an operation that marketed dietary supplements sold at Whole Foods Market, GNC, the Vitamin Shoppe, and on the Internet settled FTC charges that they made deceptive advertising claims about their supplements.
Recalls & Warnings
8/22/2012
FDA Warns of Life-Threatening Side Effects and Withdrawal Symptoms from Two Arthritis, Muscle Pain Supplements
On August 21, 2012, the FDA issued a warning to consumers about the dangers of taking Reumofan Plus and Reumofan Plus Premium, two dietary supplements marketed for arthritis, osteoporosis and muscle pain.
Recalls & Warnings
4/23/2013
Seller of Digestion, Thyroid and Vitamin D Supplements Warned For Drug Claims
On November 5, 2012, the FDA issued a warning letter to The Women's Health Institute at Texas following a review of the company's various websites which found statements made about Digest + SEB, Iodine Plus 2, and D5000 Vitamin D dietary supplements to be drug claims.
Recalls & Warnings
2/20/2013
Recall: Arthritis and Muscle Pain Supplement Contains Prescription Drugs
On February 15, 2013, Reumofan Plus USA, LLC and Reumofan USA, LLC announced a recall of Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain, because it was found to contain the active pharmaceutical ingredients methocarbamol, dexamethasone, and diclofenac.
