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Product Review

Probiotic Supplements Review (Including Pet Probiotics)

See What's Really in Probiotics and Our Top Picks

Probiotics 2025

CL Answer

I have IBS and don't want to take medication if I can help it. I've heard that peppermint works for IBS, but is there good research to support this?

Information about using peppermint oil for irritable bowel syndrome (IBS), including clinical evidence, dosage, safety and more.

Peppermint Oil for IBS? -- Bottle of peppermint oil and capsules and peppermint leaf

Product Review

Prebiotic Supplements Review

You Can't Tell How Much Fiber Is Really In Most Prebiotics Without Testing

Prebiotics 2024 Expanded Review

Product Review

L-Glutamine Supplements Review

Find the Best L-Glutamine Supplements Based on Quality and Value. See our Top Picks.

L-Glutamine Review

CL Answer

Butyrate Supplements for Gut Health: Does butyric acid really work and is it safe?

Can butyrate supplements improve gut health or help reduce symptoms of irritable bowel syndrome (IBS) or Crohn's disease? Find out what the clinical evidence shows, learn about the different forms of butyrate, including sodium butyrate, calcium-magnesium butyrate, and tributyrate, and get details about products such as BodyBio Sodium Butyrate and Healus Complete Biotic Tributyrin, dosage, safety and cost.

Butyrate Supplements

CL Answer

Has the probiotic VSL#3 been changed or discontinued? Is Visbiome a good alternative?

Find out if the probiotic formula VSL#3 has been changed and how it compares with Visbiome. ConsumerLab.com's answer explains.

VSL #3 vs. Visbiome -- box of VSL#3 and Visbiome

CL Answer

What are the benefits of Daily Synbiotic by Seed Health? Does it do what it claims, and is it better than other probiotics and prebiotics?

Review of Daily Synbiotic by Seed, including information about the prebiotic and probiotic strains in the supplement, and whether there is evidence of benefit for the synbiotic.

Person pouring Daily Synbiotic capsules from container into other hand

CL Answer

Which supplements can cause diarrhea?

Can supplements like magnesium cause diarrhea? Find out which supplements may cause diarrhea, such as vitamin B12, curcumin, magnesium, vitamin C and fish oil.

Which supplements can cause diarrhea? -- Woman with gastrointestinal pain

Product Review

Digestive Enzyme Supplements Review

Big Differences in Strength Found Among Digestive Enzyme Supplements. CL Tests Reveal Which Are Best.

CL Answer

Have you heard of the probiotic, Keybiotics? Does it do what it claims, and is it worth the money they charge?

Whole Body Research Keybiotics probiotic information, including its ingredients and possible cheaper alternatives.

Probiotics

CL Answer

How do I choose the best probiotic supplement? There are so many different strains of bacteria!

Information on how to choose the best probiotic supplement based on safety and our lab test on probiotic bacteria content.

Probiotic Supplements and Bottles Against Blue Background

CL Answer

Which supplements or OTC medications help reduce flatulence (gas), and are there any that make it worse?

Find out which supplements may help reduce flatulence (gas), and learn which supplements or foods may worsen symptoms of flatulence.

Older woman sitting on her bed and holding her stomach due to gas and bloating

CL Answer

Do any supplements help for ulcerative colitis?

Find out what supplements & vitamins can help with ulcerative colitis, such as VSL#3, curcumin, aloe or boswellia.

Woman Grabbing Stomach Due To Abdominal Discomfort

Product Review

Melatonin Supplements Review

Trouble Sleeping? See CL's Tests of Melatonin Supplements and Top Picks.

Melatonin Review 2024

CL Answer

Do any supplements help for irritable bowel syndrome (IBS)?

IBS supplements may help reduce irritable bowel symptoms such as pain, diarrhea and constipation. Supplements include probiotics, melatonin, and flaxseed.

Supplements for IBS? -- Women With Stomach Pain

CL Answer

What are the health benefits of palmitoylethanolamide (PEA), and is it safe?

Palmitoylethanolamide (PEA) is commonly promoted for its anti-inflammatory and pain-relieving effects. Find out if it works.

Woman holding her wrist due to joint pain

Product Review

Lactose Intolerance Products Review (Lactase Enzyme Supplements and Lactose-Free Milks)

Choose the Best Lactase Enzyme Supplement and Lactose-Free Milk. Find a CL Approved Lactose Intolerance Product.

Lactase Supplements Reviewed by ConsumerLab.com

Product Review

L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review

Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.

L-Tryptophan and 5-HTP (5-Hydroxy-L-tryptophan) Supplements Reviewed By Consumerlab.com

Recalls & Warnings

March 01, 2023

Seller of Dr. Miller’s Herbal “Detox” Teas Warned by FDA for Drug Claims

On February 3, 2023, the FDA issued a warning letter to Jackson Health & Wellness Clinic after inspection of the company’s website found statements about the company’s Dr. Miller’s Holy Tea, Dr. Miller’s Super Holy Tea, Dr. Miller’s Ultimate Tea, Dr.

Product Review

Manuka Honey Review

Find the Best Manuka Honey Based on Quality, Taste, and Value. See our Top Picks.

Manuka Honey Review

Product Review

Aloe Juices, Gels, and Supplements Review

How Much Aloe is Really in Aloe Products? Find Out and See Our Top Picks.

Product Review

Psyllium Fiber Supplements Review

Find the Best Psyllium Fiber Supplement and Avoid Lead.

Psyllium Review 2024

Product Review

Lavender and Tea Tree Essential Oils Review

Oils Tested for Authenticity and Purity

Product Review

Berberine and Goldenseal Supplements Review

Tests Reveal the Best and Worst Berberine and Goldenseal Products

Product Review

Iron Supplements Review (Iron Pills, Liquids and Chews)

See Which Iron Supplements Are CL's Top Picks for Different Needs

News Release

March 13, 2025

Best L-Glutamine Supplements According to ConsumerLab Tests

White Plains, NY, March 13, 2025 —  L-glutamine (glutamine) supplements are promoted to boost energy and the immune system and for other benefits, but do they really work, and if so, which glutamine products on the market are best?

News Release

November 10, 2022

Best Probiotic Supplements Identified by ConsumerLab Tests

  White Plains, New York, November 10, 2022 — Probiotic supplements can be helpful in preventing or treating constipation, diarrhea, flatulence, vaginal infections, and other conditions, but with so many different products on the market, choosing the best one is no easy task.

CL Answer

What are the health benefits of chlorophyll and chlorophyllin, and are they safe?

Chlorophyll supplements are promoted for reducing body odor, preventing cancer, removing toxins from the body, improving digestive conditions and other uses, but do they work and are they safe? Find out and learn if such supplements actually contain chlorophyll.

Woman adding drops of liquid chlorophyll to glass of water

CL Answer

Which supplements and foods help relieve constipation and which can cause constipation?

Find out which supplements can cause constipation, including iron, calcium, protein powders and drinks and others. ConsumerLab.com's answer explains.

Which supplements can cause constipation? -- Woman with gastrointestinal pain

CL Answer

What are the health benefits of bovine colostrum and is it safe?

Bovine colostrum is promoted for boosting immunity, preventing and treating diarrhea, and improving gut health, but does it really work? See the clinical evidence for bovine colostrum, including doses that have been used, as well as safety concerns, cost considerations, and the difference between regular bovine colostrum and hyperimmune bovine colostrum.

Bovine colostrum powder and capsule supplements

CL Answer

Which supplements and foods reduce or increase the risk of kidney stones?

Find out which supplements, foods and beverages may increase or decrease the risk of kidney stones, including information about potassium, calcium, choline, turmeric and curcumin, vitamin C, as well as foods and beverages such as green tea, lemon juice, orange juice, cranberry juice, chocolate and almonds.

Supplements for Kidney Stones

CL Answer

Is it better to take fish oil, flaxseed oil -- or both?

Fish oil and flaxseed oil -- how they are different, what they are used for, if and how they can help with arthritis, depression, lowering cholesterol & more.

Flaxseed Oil vs Fish Oil -- Omega-3 Supplements

CL Answer

Does Magnesi-Om Work and Is It Worth It?

Magnesi-Om's website claims it can promote calmness and improve cognitive function, muscle relaxation, and bowel movements. Find out if it's been shown to work, is safe, and worth the price.

Bottle of Magnesi-Om

CL Answer

Which supplements, foods or diet and lifestyle changes help relieve acid reflux (heartburn), and which worsen it?

Find out which supplements and foods can help relieve acid reflux, and which can make it worse.

Supplements Making Acid Reflux Worse -- Man with acid reflux pain

News Release

October 28, 2022

Labels on Prebiotic Supplements Are Often Unreliable, Tests Show

  White Plains, New York, October 28, 2022 — Prebiotic supplements provide fiber that feed beneficial bacteria in the gut. However, recent ConsumerLab tests show that consumers often can’t rely on labels to know how much prebiotic fiber is really in products.

CL Answer

Do any supplements help reduce menstrual pain or symptoms of premenstrual syndrome (PMS)?

Find out which supplements help reduce premenstrual syndrome (PMS) symptoms, such as mood swings, pain, bloating, irritability and food cravings.

Woman in PJs Holding Stomach from Abdominal Pain

CL Answer

Which supplements can help treat anemia? Do any supplements cause a low red blood cell count?

Find out which vitamin and nutrient supplements can help prevent and treat anemia in people who are nutrient deficient and learn which supplements may cause low blood cell counts, especially when used in excess.

Woman holding various vitamins and supplements in her hands

CL Answer

What is BPC-157, what is it used for and is it safe?

Find out about BPC-157, including what it's promoted for and if it is safe.

White capsules vials and a syringe on a blue background

News Release

April 14, 2020

ConsumerLab Tests Reveal Best Probiotic Supplements and Those With Quality Issues

White Plains, New York, April 14, 2020 — Probiotic supplements may be helpful for conditions including antibiotic-associated diarrhea, irritable bowel syndrome, and respiratory infections.

News Release

July 31, 2018

Best L-Tryptophan and 5-HTP Supplements Identified by ConsumerLab -- ConsumerLab Tests Strength and Purity of Supplements for Sleep and Mood

White Plains, New York, July 31, 2018 — L-tryptophan supplements are often promoted to improve sleep and 5-HTP supplements to help with depression.

News Release

May 02, 2018

Best Probiotic Supplements and Kombuchas? -- ConsumerLab Tests 41 Popular Products, Reveals Problems and Top Picks

White Plains, New York, May 2, 2018 — With so many different probiotic supplements on the market, each providing different amounts and strains of beneficial bacteria or yeast, choosing the right one can be an overwhelming task.

News Release

February 13, 2014

Calcium, Vitamin C, and Fish Oil Supplements Drop in Use, Probiotics Rise According to ConsumerLab.com Survey

White Plains, New York, February 13, 2014 — A recent survey of over 10,000 people who use dietary supplements shows that the use of calcium, vitamin C and fish oil supplements fell during 2013 while the use of probiotics increased.

CL Answer

Are There Supplements That Help Treat POTS (Postural Orthostatic Tachycardia Syndrome)?

Find out which supplements and lifestyle changes may be helpful for people with Postural Orthostatic Tachycardia Syndrome (POTS).

POTS

CL Answer

Can zuPOO and its primary ingredient, cascara sagrada, cleanse the gut, improve digestion and help with weight management?

zuPOO is marketed for gut support and as a colon cleanser for weight management. Find out if research supports these claims and if ingredients in zuPOO are safe.

zuPOO supplement bottle with white background

CL Answer

Hemp Seeds: Health Benefits, Safety, and What To Consider When Picking a Product

Hemp seeds are promoted for heart health, diabetes, boosting testosterone, and other conditions, but do they work? Find out and learn about potential safety concerns.

Whole hemp seeds and hemp hearts in small white bowls

CL Answer

Do any supplements help with restless legs syndrome?

Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS). ConsumerLab.com's answer explains.

Supplements for Restless Legs Syndrome

CL Answer

I developed a rash soon after starting a probiotic. Is it possible to be allergic to probiotics?

Find out if probiotics can cause allergic reactions, including skin rashes, and why.

Young Woman Scratching Forearm

CL Answer

Do any supplements or foods benefit people with Crohn's disease? Are there any supplements that should be avoided?

Find out the most common vitamin and mineral deficiencies in people with Crohn's disease, including iron, B6, B12, vitamin D, zinc and others, plus evidence for N-acetyl-glucosamine (NAG), fish oil, and curcumin.

Supplements for Crohn's Disease -- Crohn's Disease Written on Notepad, Pills

News Release

August 31, 2012

ConsumerLab.com tests selenium supplements -- Finds one with less than 25% of listed amount

White Plains, New York, August 31, 2012 — ConsumerLab.com announced results today of its Product Review of Selenium Supplements. Among the supplements selected by ConsumerLab.com for testing, one was found to contain only 23.

News Release

February 09, 2012

Probiotics grow in popularity but don't always deliver on promises says ConsumerLab.com -- New report provides guidance to consumers

White Plains, New York, February 9, 2012 — Probiotic supplements and foods containing "friendly" bacteria or yeast have become popular options for people hoping to improve bowel function or boost immunity. But many customers are confused by the vast array of choices.

News Release

November 16, 2009

ConsumerLab.com finds many probiotics don't deliver listed ingredients

White Plains, New York November 16, 2009 — Many probiotic supplements do not contain the number of viable organisms listed on their labels according to a new report from ConsumerLab.com.

CL Answer

I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?

Learn about Prozac (fluoxetine) drug interactions along with other supplements and SSRIs.

Woman Taking Pill with Glass of Water

CL Answer

What are the health benefits of zinc carnosine, also called polaprezinc, and is it safe?

Find out if zinc carnosine is beneficial for any GI conditions, including stomach ulcers, Helicobacter pylori infection, taste disturbances, aspirin-induced small-bowel injury and oral mucositis, and learn if it is safe.

Zinc carnosine supplements in wooden spoon in front of oysters

Recalls & Warnings

April 23, 2013

Seller of Digestion, Thyroid and Vitamin D Supplements Warned For Drug Claims

On November 5, 2012, the FDA issued a warning letter to The Women's Health Institute at Texas following a review of the company's various websites which found statements made about Digest + SEB, Iodine Plus 2, and D5000 Vitamin D dietary supplements to be drug claims.

Recalls & Warnings

December 17, 2020

FTC Crackdown on Six Deceptive CBD Products

On December 17, 2020, the FTC announced that it is taking action against six companies for selling CBD products with unsupported and deceptive health claims that they can treat a variety of conditions, including cancer, heart disease, hypertension, Alzheimer's disease, and others.

News Release

August 04, 2009

Most vitamin E supplements pass testing, but what seems natural may be synthetic according to ConsumerLab.com -- New review of vitamin E supplements, oils, and creams released today

White Plains, New York — November 16, 2009 — Many probiotic supplements do not contain the number of viable organisms listed on their labels according to a new report from ConsumerLab.com.

Recalls & Warnings

November 02, 2012

Maker of Joint Health, Blood Sugar, Prostate, Ginkgo Supplements and More Warned For Drug Claims, Misbranding and Adulteration

On September 10, 2012, the FDA issued a warning letter to Global Source Management & Consulting for making drug claims about the following dietary supplements: Scientific Joint Program capsules, Alpha Lipoic Acid, Healthy Blood Sugar Diabetic Support, Dr.

Recalls & Warnings

March 16, 2006

Garden of Life, Maker of Primal Defense, Settles FTC Charges

On March 9, 2006, The Federal Trade Commission (FTC) announced that an operation that marketed dietary supplements sold at Whole Foods Market, GNC, the Vitamin Shoppe, and on the Internet settled FTC charges that they made deceptive advertising claims about their supplements.

Recalls & Warnings

September 14, 2021

Seller of Lion's Mane, Other Mushroom Supplements Warned by FDA

On July 20, 2021, the FDA issued a warning letter to Brilliant Enterprises LLC because it found statements made on the company's website and social media about mushroom supplements, including Lion's Mane, BoomChaga, CordaCex, and LVL:MAX to be drug claims.

News Release

December 12, 2006

Probiotic supplements grow in popularity but viable bacteria missing in many — ConsumerLab.com cautions consumers to select probiotics carefully and store them properly

WHITE PLAINS, NEW YORK — DECEMBER 12, 2006 — Sales of supplements containing beneficial organisms (probiotics) have grown rapidly, but a new test report from ConsumerLab.com shows that 44% contained fewer viable organisms than claimed or generally known to be effective.

Recalls & Warnings

September 13, 2013

Metagenics Warned For Misbranding of Medical Foods and Drug Claims

On August 13, 2013, the FDA issued a warning letter to Metagenics, Inc.

Recalls & Warnings

June 02, 2022

Walmart Inc. Recalls Joint Supplements With Omega-3, Glucosamine & Curcumin

On May 28, 2022, Walmart Inc. issued a voluntary recall of all lots of Artri Ajo King Joint Supplements after FDA laboratory analysis found the presence of undeclared diclofenac.

Recalls & Warnings

February 22, 2021

FDA Warns Seller of Melatonin & Other Sleep Supplements

On February 18, 2021, the FDA issued a warning letter to SANA Group LLC following a review of the company's website, which found statements made about the company's products Sleep Sana Sleep Drops and Sleep Shots to be drug claims.

Recalls & Warnings

November 29, 2016

Seller of Mineral, Joint Supplements and More Warned for Manufacturing Violations, Drug Claims

On July 1, 2016, the FDA issued a warning letter to BioGenyx-Basic Reset, following a facility inspection which found the company's products, including Ionyte, Aqualyte, Beta Factor, Bee Gold and Primo Java to be adulterated because they were prepared, packed, or held under ...

Recalls & Warnings

April 17, 2020

Seller of Vitamin D, MSM, Selenium & More Warned for Drug Claims

On March 31, 2020, the FDA issued a warning letter to KetoKerri LLC following a review of the company's website, which found statements made about some of the company's products, including Dr.

Recalls & Warnings

October 24, 2012

Manufacturer of Green Tea, Vitamin E, Omega-3 and Cranberry Supplements Warned For Manufacturing Violations, Misbranding and Drug Claims

On October 16, 2012, the FDA issued a warning letter to dietary supplement manufacturer Advanced Nutritional Technology Inc.

Recalls & Warnings

December 21, 2012

Dangerous Supplement Being Sold Under New Name

On December 21, 2012, the FDA warned consumers that Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain that has been linked to serious and sometimes fatal side effects, is now being sold under the name WOW.

Recalls & Warnings

February 20, 2013

Recall: Arthritis and Muscle Pain Supplement Contains Prescription Drugs

On February 15, 2013, Reumofan Plus USA, LLC and Reumofan USA, LLC announced a recall of Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain, because it was found to contain the active pharmaceutical ingredients methocarbamol, dexamethasone, and diclofenac.

Recalls & Warnings

August 22, 2012

FDA Warns of Life-Threatening Side Effects and Withdrawal Symptoms from Two Arthritis, Muscle Pain Supplements

On August 21, 2012, the FDA issued a warning to consumers about the dangers of taking Reumofan Plus and Reumofan Plus Premium, two dietary supplements marketed for arthritis, osteoporosis and muscle pain.