A large study found that people with higher intakes of choline from their diets had a higher risk of death, specifically cardiovascular death, than people with lower choline intakes. Should you be concerned? See the Concerns and Cautions section of the Choline Supplements Review.
An unusual type of kidney stone has been reported in several people who regularly consumed large amounts of a vitamin and amino acid supplement containing a particular form of choline and vitamin C. For details, see the Concerns and Cautions section of the Choline Supplements Review.
It was recommended last year that women take a choline supplement when pregnant. Adding momentum to this recommendation is a recent study showing that giving pregnant women a larger amount of choline than normally considered adequate resulted in improved information processing speeds in their infants. Currently, choline is not found in most prenatal vitamins. For more information, see the During Pregnancy and Lactation section of the Choline Supplements Review. (Also see our Top Picks among products.)
The American Medical Association recently voted to recommend that all prenatal vitamins include appropriate amounts of choline. Getting adequate choline may reduce the risk of birth defects in children, but most women don’t get enough and prenatal vitamins typically provide little to none. Find out how to get adequate choline from supplements and/or foods in the Choline Supplements Review, which includes our Top Picks. Also see the "Prenatal Vitamin" section of the Multivitamin Supplements Review.
A recent study found that taking choline supplements increased the tendency for platelets to aggregate, a risk factor for heart disease, suggesting that choline supplements should be avoided. For details see the Concerns and Cautions section of the Choline Supplements Review >>